KLC3
kinesin light chain 3
Summary
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]
Known Variants64 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs10404465 | 19:45,843,609 | T/G | — | — |
| rs780895997 | 19:45,848,816 | C/T | — | uncertain significance |
| rs2513974791 | 19:45,848,837 | T/C | — | uncertain significance |
| rs376299711 | 19:45,848,905 | G/A | — | uncertain significance |
| rs770498926 | 19:45,848,912 | G/A | — | uncertain significance |
| rs762027896 | 19:45,848,956 | G/A | — | uncertain significance |
| rs765389608 | 19:45,848,957 | C/T | — | uncertain significance |
| rs569097340 | 19:45,848,969 | C/T | — | uncertain significance |
| rs890899037 | 19:45,848,977 | G/A | — | uncertain significance |
| rs769289827 | 19:45,849,049 | G/A | — | uncertain significance |
| rs1971494937 | 19:45,849,809 | T/C | — | uncertain significance |
| rs944803977 | 19:45,849,874 | C/T | — | uncertain significance |
| rs764933269 | 19:45,849,901 | C/T | — | uncertain significance |
| rs1400102735 | 19:45,849,937 | G/A | — | uncertain significance |
| rs750192790 | 19:45,849,970 | G/A | — | uncertain significance |
| rs766315749 | 19:45,849,972 | G/T | — | uncertain significance |
| rs201298939 | 19:45,849,975 | G/T | — | uncertain significance |
| rs1283840412 | 19:45,849,985 | G/C | — | uncertain significance |
| rs1009407150 | 19:45,850,013 | A/C | — | uncertain significance |
| rs76874841 | 19:45,850,019 | C/T | — | uncertain significance |
| rs768255510 | 19:45,850,723 | C/T | — | uncertain significance |
| rs558805867 | 19:45,850,742 | C/T | — | uncertain significance |
| rs373228076 | 19:45,850,755 | C/A | — | uncertain significance |
| rs780908090 | 19:45,851,210 | G/A | — | uncertain significance |
| rs367618092 | 19:45,851,261 | C/T | — | uncertain significance |
| rs750506615 | 19:45,851,262 | G/A | — | uncertain significance |
| rs374861234 | 19:45,851,279 | G/A | — | uncertain significance |
| rs2513979020 | 19:45,851,283 | T/A | — | uncertain significance |
| rs750137771 | 19:45,851,355 | G/A | — | uncertain significance |
| rs1262084780 | 19:45,851,363 | G/A | — | uncertain significance |
| rs35030295 | 19:45,851,924 | A/C | — | uncertain significance |
| rs2513980190 | 19:45,851,939 | T/C | — | uncertain significance |
| rs372026834 | 19:45,851,969 | C/T | — | uncertain significance |
| rs1030136012 | 19:45,852,082 | C/T | — | uncertain significance |
| rs373683799 | 19:45,852,123 | G/A | — | uncertain significance |
| rs199706544 | 19:45,852,132 | C/T | — | uncertain significance |
| rs1263802046 | 19:45,852,139 | C/T | — | uncertain significance |
| rs139080813 | 19:45,852,156 | C/T | — | uncertain significance |
| rs1481128884 | 19:45,852,159 | G/A | — | uncertain significance |
| rs552170468 | 19:45,852,381 | C/T | — | — |
| rs750327090 | 19:45,852,706 | C/T | — | uncertain significance |
| rs760262930 | 19:45,852,777 | C/T | — | uncertain significance |
| rs1223638276 | 19:45,852,784 | A/G | — | uncertain significance |
| rs759094002 | 19:45,852,789 | C/T | — | uncertain significance |
| rs2513987614 | 19:45,853,602 | T/G | — | uncertain significance |
| rs755453083 | 19:45,853,619 | G/C | — | uncertain significance |
| rs781486330 | 19:45,853,621 | A/G | — | uncertain significance |
| rs199738278 | 19:45,853,801 | G/A | — | likely benign |
| rs2513988508 | 19:45,853,806 | A/C | — | uncertain significance |
| rs201950695 | 19:45,853,905 | C/T | — | uncertain significance |
| rs369584425 | 19:45,853,906 | G/A | — | uncertain significance |
| rs1040897551 | 19:45,853,924 | C/T | — | uncertain significance |
| rs375060034 | 19:45,853,933 | G/A | — | uncertain significance |
| rs199586485 | 19:45,853,978 | G/A | — | uncertain significance |
| rs370566239 | 19:45,853,988 | G/A | — | likely benign |
| rs752348371 | 19:45,853,990 | C/T | — | uncertain significance |
| rs757858424 | 19:45,853,996 | G/A | — | uncertain significance |
| rs755377157 | 19:45,854,226 | T/C | — | uncertain significance |
| rs371326680 | 19:45,854,246 | G/A | — | uncertain significance |
| rs201873145 | 19:45,854,559 | C/A | — | uncertain significance |
| rs201702505 | 19:45,854,575 | G/A | — | uncertain significance |
| rs373906614 | 19:45,854,585 | C/T | — | likely benign |
| rs368153383 | 19:45,854,586 | G/A | — | conflicting classifications of pathogenicity |
| rs561464436 | 19:45,854,610 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.