LSM6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
Summary
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]
Known Variants3 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs6537401 | 4:147,099,654 | G/A | intron variant | — |
| rs2547064397 | 4:147,104,079 | T/G | — | uncertain significance |
| rs2547067682 | 4:147,108,534 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.