rs6537401

This is a intron variant variant in the LSM6 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

attention deficit hyperactivity disorder

Demontis D et al. “Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.” Nature Genetics 55(2):198-208 (2023)

Allele G

OR 0.94

p 1.0e-8

N 225,534

Large GWAS

European

About LSM6

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]

View all LSM6 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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