LYPLAL1
lysophospholipase like 1
Summary
Enables palmitoyl-(protein) hydrolase activity. Involved in negative regulation of cGAS/STING signaling pathway. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants38 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs75060212 | 1:219,345,611 | T/G | upstream gene variant | — |
| rs762618682 | 1:219,347,261 | A/C | — | uncertain significance |
| rs372613753 | 1:219,347,271 | C/G | — | uncertain significance |
| rs145702163 | 1:219,347,296 | G/A | — | uncertain significance |
| rs1037557668 | 1:219,347,302 | C/T | — | likely benign |
| rs2527891299 | 1:219,347,303 | T/C | — | uncertain significance |
| rs1462066465 | 1:219,352,546 | C/T | — | uncertain significance |
| rs545185290 | 1:219,352,559 | A/G | — | uncertain significance |
| rs6701914 | 1:219,360,899 | T/G | — | — |
| rs777326480 | 1:219,366,456 | A/G | — | uncertain significance |
| rs751333669 | 1:219,366,486 | A/G | — | uncertain significance |
| rs17049143 | 1:219,377,340 | G/A | — | — |
| rs763668958 | 1:219,383,945 | T/G | — | uncertain significance |
| rs2528272042 | 1:219,384,837 | C/T | — | uncertain significance |
| rs747025177 | 1:219,384,842 | G/T | — | uncertain significance |
| rs757530334 | 1:219,384,847 | G/A | — | likely benign |
| rs570275364 | 1:219,384,901 | T/C | — | uncertain significance |
| rs34201999 | 1:219,384,945 | C/G | — | benign |
| rs145100238 | 1:219,385,014 | A/G | — | uncertain significance |
| rs1226726357 | 1:219,385,029 | A/G | — | uncertain significance |
| rs6690020 | 1:219,430,183 | C/A | intergenic variant | — |
| rs61836088 | 1:219,436,122 | T/G | — | — |
| rs12137855 | 1:219,448,378 | C/T | intergenic variant | — |
| rs7536147 | 1:219,451,442 | A/G | intergenic variant | — |
| rs6676688 | 1:219,458,919 | G/A | intergenic variant | — |
| rs11118267 | 1:219,482,371 | G/A | intergenic variant | — |
| rs75128958 | 1:219,483,218 | G/A | intergenic variant | — |
| rs6668147 | 1:219,511,963 | A/C | intergenic variant | — |
| rs13376087 | 1:219,520,895 | C/T | intergenic variant | — |
| rs13376300 | 1:219,522,662 | C/A | intergenic variant | — |
| rs11118284 | 1:219,530,243 | G/T | intergenic variant | — |
| rs12128471 | 1:219,534,485 | G/A | intergenic variant | — |
| rs6691931 | 1:219,560,818 | C/A | — | — |
| rs2791554 | 1:219,572,348 | C/T | intergenic variant | — |
| rs2791555 | 1:219,573,315 | C/G | — | — |
| rs2018076 | 1:219,585,279 | G/T | coding sequence variant | — |
| rs74139185 | 1:219,612,185 | A/G | intron variant | — |
| rs61838776 | 1:219,618,564 | C/A | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.