MAPKAP1

MAPK associated protein 1

Summary

This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008]

Known Variants32 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs1441208408	9:128,201,224	T/G	—	uncertain significance
rs111458512	9:128,201,271	C/T	—	benign
rs555771876	9:128,206,796	T/C	—	uncertain significance
rs35549826	9:128,206,855	C/T	—	benign
rs752861508	9:128,206,869	T/C	—	uncertain significance
rs199955511	9:128,221,686	C/T	—	—
rs10986769	9:128,222,340	A/T	—	—
rs2541780874	9:128,230,325	C/A	—	uncertain significance
rs10121005	9:128,252,604	A/G	intron variant	—
rs1357279093	9:128,268,636	G/C	—	uncertain significance
rs11542134	9:128,305,390	T/C	—	benign
rs536861	9:128,313,444	A/C	intron variant	—
rs1830838274	9:128,322,020	G/A	—	uncertain significance
rs13294217	9:128,326,190	C/T	upstream gene variant	—
rs377752331	9:128,347,904	C/T	—	uncertain significance
rs757433296	9:128,347,973	C/G	—	uncertain significance
rs12554256	9:128,385,423	G/T	—	—
rs473426	9:128,406,988	C/G	—	benign
rs376993327	9:128,420,018	C/G	—	uncertain significance
rs2538318247	9:128,420,055	C/T	—	uncertain significance
rs4838281	9:128,431,502	G/A	intron variant	—
rs201151787	9:128,434,756	T/C	—	uncertain significance
rs2538354205	9:128,434,759	A/G	—	uncertain significance
rs142713473	9:128,434,806	C/T	—	likely benign
rs144290254	9:128,434,810	C/T	—	uncertain significance
rs1403717933	9:128,434,823	G/C	—	uncertain significance
rs148740501	9:128,434,832	T/C	—	uncertain significance
rs77961302	9:128,451,741	A/C	—	—
rs13296765	9:128,455,859	T/C	intron variant	—
rs138286128	9:128,455,969	T/C	—	—
rs62567183	9:128,456,117	T/C	—	—
rs752493195	9:128,468,344	A/G	—	—

Gene information from NCBI Gene. Variant classifications from ClinVar.