MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
Summary
Predicted to be involved in regulation of synapse organization and spinal cord motor neuron differentiation. Predicted to act upstream of or within several processes, including motor behavior; negative regulation of neuron apoptotic process; and neuron migration. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic density membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants46 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1235 | 14:47,309,496 | G/T | downstream gene variant | — |
| rs12879453 | 14:47,309,879 | A/C | — | — |
| rs1880630939 | 14:47,311,156 | G/A | — | uncertain significance |
| rs2933211 | 14:47,313,541 | G/A | intron variant | — |
| rs2933213 | 14:47,318,777 | C/T | intron variant | — |
| rs2502573087 | 14:47,342,779 | A/C | — | uncertain significance |
| rs2502575839 | 14:47,343,322 | T/C | — | uncertain significance |
| rs2502718728 | 14:47,389,250 | C/T | — | uncertain significance |
| rs778588739 | 14:47,389,286 | T/A | — | uncertain significance |
| rs73237216 | 14:47,402,789 | T/A | intron variant | — |
| rs12883384 | 14:47,403,684 | A/T | — | — |
| rs76888297 | 14:47,426,686 | C/G | — | benign |
| rs373296594 | 14:47,426,790 | C/T | — | uncertain significance |
| rs11627056 | 14:47,454,986 | G/A | regulatory region variant | — |
| rs2503092639 | 14:47,504,427 | C/T | — | uncertain significance |
| rs961616 | 14:47,521,489 | T/A | — | — |
| rs779032374 | 14:47,530,612 | C/G | — | likely benign |
| rs2503180337 | 14:47,530,731 | C/T | — | uncertain significance |
| rs2503308681 | 14:47,566,084 | T/C | — | uncertain significance |
| rs200459170 | 14:47,566,145 | G/A | — | benign |
| rs2502537728 | 14:47,600,936 | A/C | — | uncertain significance |
| rs73248044 | 14:47,600,946 | A/G | — | benign |
| rs2502538055 | 14:47,600,956 | G/A | — | uncertain significance |
| rs2502597856 | 14:47,613,387 | A/G | — | uncertain significance |
| rs2502598465 | 14:47,613,475 | A/T | — | uncertain significance |
| rs17118176 | 14:47,685,859 | A/G | intron variant | — |
| rs2502969829 | 14:47,687,251 | T/C | — | uncertain significance |
| rs984675150 | 14:47,687,261 | C/A | — | likely benign |
| rs77012147 | 14:47,761,992 | C/G | intron variant | — |
| rs2503280763 | 14:47,770,691 | A/C | — | uncertain significance |
| rs187498428 | 14:47,770,699 | T/C | — | uncertain significance |
| rs2297926 | 14:47,774,501 | G/C | — | — |
| rs2416054 | 14:47,824,521 | C/A | — | — |
| rs7159841 | 14:47,863,835 | C/G | — | — |
| rs17118552 | 14:47,874,557 | A/G | intron variant | — |
| rs189025428 | 14:47,901,391 | G/C | intron variant | — |
| rs187636472 | 14:47,915,125 | A/G | upstream gene variant | — |
| rs7159376 | 14:47,921,389 | A/G | — | — |
| rs2416083 | 14:47,935,940 | G/C | — | — |
| rs1160351 | 14:48,015,982 | A/T | — | — |
| rs7144383 | 14:48,040,375 | G/A | intron variant | — |
| rs4143912 | 14:48,054,159 | A/T | — | — |
| rs79618977 | 14:48,083,441 | T/A | intron variant | — |
| rs8004608 | 14:48,087,414 | T/C | — | — |
| rs8006270 | 14:48,105,875 | C/T | — | — |
| rs138459260 | 14:48,134,801 | G/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.