MGA

MAX dimerization protein MGA

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Part of MLL1 complex. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants59 total

rsidPosition (GRCh37)AllelesClassClinVar
rs802331115:41,911,805C/G——
rs1163924915:41,914,597G/A——
rs2852668915:41,927,330G/C——
rs803017915:41,929,220A/C——
rs1163210015:41,946,620G/T——
rs241262315:41,960,323A/Cintron variant—
rs19958518715:41,961,191T/C—likely benign
rs20031934815:41,961,299T/G—uncertain significance
rs77650221915:41,961,926C/A—uncertain significance
rs76499109615:41,961,931A/C—uncertain significance
rs18218797415:41,962,080C/G—likely benign
rs77818350915:41,962,086T/C—uncertain significance
rs380334815:41,962,104A/G—likely benign
rs36980257815:41,965,961G/A——
rs716453315:41,966,731T/Aintron variant—
rs446558415:41,971,901C/A——
rs77670569915:41,988,506T/G—uncertain significance
rs19966663515:41,988,709A/G—likely benign
rs77368108615:41,988,765C/T—likely benign
rs14064221615:41,989,025C/T—likely benign
rs11361707515:41,989,230G/T—benign
rs217800415:41,991,315A/Gmissense variant—
rs206035068415:42,003,004T/A—uncertain significance
rs6173606415:42,005,480C/T—benign
rs53697597315:42,010,505A/G——
rs257795515:42,012,178C/A——
rs295044615:42,012,724T/A——
rs11718316115:42,015,575A/Gupstream gene variant—
rs36851338315:42,019,518C/T—uncertain significance
rs75551031515:42,019,549A/G—uncertain significance
rs14010444615:42,019,610T/A—benign
rs52950205815:42,021,386G/A—uncertain significance
rs159588950815:42,021,437G/C—likely pathogenic
rs132615411815:42,021,454C/T—likely benign
rs717112315:42,026,363C/Tregulatory region variant—
rs76298809515:42,028,431T/C—likely benign
rs5903080415:42,028,697C/G—benign
rs6173606815:42,028,805A/G—benign
rs269516715:42,028,820G/A—benign
rs20049801715:42,032,326G/A—likely benign
rs11179345615:42,035,042T/C—likely benign
rs257794715:42,037,570C/A——
rs127612928015:42,040,942C/A—uncertain significance
rs255100013215:42,040,981A/G—uncertain significance
rs6173607215:42,041,088C/A—benign
rs206270915215:42,041,677T/C—uncertain significance
rs6175723515:42,041,750A/G—benign
rs76973533715:42,041,854T/G—uncertain significance
rs206273848315:42,042,066G/C—uncertain significance
rs257795615:42,049,978T/C—benign
rs76115292515:42,052,527C/A—uncertain significance
rs14307546015:42,057,152C/T—uncertain significance
rs2851008815:42,057,268G/A—benign
rs11157628315:42,058,500A/G—benign
rs147464943615:42,058,717A/G—uncertain significance
rs11643907415:42,058,900A/G—benign
rs19977999715:42,058,958A/C—likely benign
rs94436366515:42,059,143C/T—uncertain significance
rs37579727915:42,059,339A/G—uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.