MGAT3
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Summary
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Known Variants31 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs113200473 | 22:39,853,740 | G/A | regulatory region variant | — |
| rs2006987 | 22:39,855,082 | T/C | — | — |
| rs909674 | 22:39,859,169 | C/G | — | — |
| rs7286917 | 22:39,860,868 | A/G | intron variant | — |
| rs760713 | 22:39,875,595 | G/C | upstream gene variant | — |
| rs1023137384 | 22:39,883,365 | C/G | — | uncertain significance |
| rs775848158 | 22:39,883,383 | A/G | — | uncertain significance |
| rs2517976397 | 22:39,883,482 | A/C | — | uncertain significance |
| rs145791006 | 22:39,883,564 | G/A | — | uncertain significance |
| rs200726619 | 22:39,883,576 | A/G | — | uncertain significance |
| rs979603674 | 22:39,883,797 | C/A | — | uncertain significance |
| rs776299748 | 22:39,883,800 | C/G | — | uncertain significance |
| rs762648519 | 22:39,883,815 | G/A | — | likely benign |
| rs754931655 | 22:39,883,828 | C/G | — | uncertain significance |
| rs368932308 | 22:39,883,878 | G/A | — | uncertain significance |
| rs1281251179 | 22:39,883,912 | T/A | — | uncertain significance |
| rs201916942 | 22:39,883,927 | A/C | — | uncertain significance |
| rs558250058 | 22:39,883,974 | G/A | — | uncertain significance |
| rs1287462754 | 22:39,884,117 | G/C | — | uncertain significance |
| rs753015998 | 22:39,884,274 | C/G | — | uncertain significance |
| rs139812692 | 22:39,884,279 | C/T | — | benign |
| rs142504494 | 22:39,884,357 | C/G | — | benign |
| rs2145728750 | 22:39,884,466 | G/A | — | likely benign |
| rs371172729 | 22:39,884,531 | A/C | — | uncertain significance |
| rs2517978764 | 22:39,884,667 | G/A | — | likely benign |
| rs141333537 | 22:39,884,765 | G/C | — | uncertain significance |
| rs148319429 | 22:39,884,826 | G/C | — | uncertain significance |
| rs1207257006 | 22:39,884,892 | C/T | — | uncertain significance |
| rs769431587 | 22:39,884,919 | C/T | — | uncertain significance |
| rs766150345 | 22:39,884,929 | G/A | — | uncertain significance |
| rs751551105 | 22:39,884,940 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.