MIAT
myocardial infarction associated transcript
Summary
This gene encodes a spliced long non-coding RNA that may constitute a component of the nuclear matrix. Altered expression of this locus has been reported to be associated with a susceptibility to myocardial infarction. It has also been proposed that pathways involving this transcript may contribute to the pathophysiology of schizophrenia. A similar gene in mouse has been associated with retinal cell fate determination. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2014]
Known Variants16 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs563910796 | 22:27,058,247 | C/T | — | — |
| rs2331291 | 22:27,058,821 | C/T | downstream gene variant | risk factor |
| rs62224896 | 22:27,062,296 | G/A | — | benign |
| rs73163288 | 22:27,062,592 | G/A | — | benign |
| rs2301523 | 22:27,062,669 | G/A | coding sequence variant | risk factor |
| rs1275309058 | 22:27,062,753 | G/T | — | benign |
| rs34403716 | 22:27,064,576 | G/A | — | no classification for the single variant |
| rs35955962 | 22:27,065,224 | G/A | — | no classification for the single variant |
| rs2517481346 | 22:27,065,734 | G/C | — | benign |
| rs2517481704 | 22:27,065,845 | G/C | — | likely benign |
| rs73163297 | 22:27,066,734 | T/C | — | benign |
| rs2517485908 | 22:27,067,223 | G/T | — | benign |
| rs188631416 | 22:27,067,791 | C/T | — | benign |
| rs2517488263 | 22:27,068,051 | A/T | — | benign |
| rs1311858850 | 22:27,068,152 | C/T | — | benign |
| rs1931130846 | 22:27,069,253 | G/T | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.