Trait
SNPs associated with Dementia
33 genetic variants across 11 genes have been associated with Dementia in published research. Key genes include ABCA7, ACE, APOE.
Associated variants33 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs429358 | APOE | GWAS association (p=7.0e-305) | Meta-analysis |
| rs4663105 | — | GWAS association (p=6.0e-34) | Meta-analysis |
| rs10402524 | — | GWAS association (p=1.0e-17) | Meta-analysis |
| rs744373 | BIN1 | GWAS association (p=2.0e-17) | Meta-analysis |
| rs12453 | — | GWAS association (p=1.0e-16) | Meta-analysis |
| rs2278867 | MS4A6A | GWAS association (p=2.0e-15) | Meta-analysis |
| rs4844610 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs1408077 | CR1 | GWAS association (p=5.0e-10) | Meta-analysis |
| rs2208524 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs11691153 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs6853262 | — | GWAS association (p=6.0e-09) | Meta-analysis |
| rs2677386 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs2906644 | — | GWAS association (p=8.0e-09) | Meta-analysis |
| rs7006786 | — | GWAS association (p=9.0e-09) | Meta-analysis |
| rs35483531 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs3764650 | ABCA7 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs170084 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs10940421 | LINC02998 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs79045532 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs138908633 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs74435987 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs11225924 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs9323877 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs113747850 | MAPK9 | GWAS association (p=5.0e-08) | Meta-analysis |
| rs728986 | FLT4 | GWAS association (p=5.0e-08) | Meta-analysis |
| rs10792832 | — | GWAS association (p=8.0e-14) | Meta-analysis |
| rs10948367 | — | GWAS association (p=4.0e-13) | Meta-analysis |
| rs4295 | ACE | GWAS association (p=1.0e-11) | Meta-analysis |
| rs6857 | NECTIN2 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs730482 | — | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs526904 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs563910796 | MIAT | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs148377161 | — | GWAS association (p=1.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.