rs728986
This variant is located in the FLT4 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
dementia
“A genome-wide association meta-analysis of all-cause and vascular dementia.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 20(9):5973-5995 (2024)
Allele A
OR —
β 0.087
p 5.0e-8
N 524,852
Meta-analysisLarge GWAS
multi-ancestry
▶ClinVar annotation
Benign★☆☆☆
1 submitterAbout FLT4
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]
View all FLT4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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