MIR17HG

miR-17-92a-1 cluster host gene

Summary

This gene is the host gene for the MIR17-92 cluster, a group of at least six microRNAs (miRNAs) that may be involved in cell survival, proliferation, differentiation, and angiogenesis. Amplification of this gene has been found in several lymphomas and solid tumors. Two non-protein coding transcript variants have been found for this host gene, but only the longest is a polycistronic transcript containing the MIR17-92 cluster. [provided by RefSeq, May 2012]

Known Variants21 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs138151712	13:92,000,026	G/C	regulatory region variant	—
rs994382198	13:92,002,003	A/C	—	uncertain significance
rs181587881	13:92,002,147	A/G	—	likely benign
rs112107109	13:92,002,256	C/T	—	likely benign
rs140053713	13:92,002,647	C/G	—	benign
rs373341333	13:92,002,805	A/G	—	likely benign
rs182442873	13:92,003,098	A/G	—	likely benign
rs562884140	13:92,003,261	G/T	—	likely benign
rs139418718	13:92,003,809	C/T	—	likely benign
rs1034074756	13:92,004,975	C/T	—	uncertain significance
rs111371822	13:92,005,134	A/G	regulatory region variant	—
rs7336610	13:92,005,137	T/C	—	benign
rs149052230	13:92,005,333	C/T	—	likely benign
rs1875410050	13:92,005,395	C/A	—	likely benign
rs7318578	13:92,005,469	C/A	regulatory region variant	—
rs1200989960	13:92,005,638	A/G	—	likely benign
rs1339111235	13:92,005,886	A/G	—	uncertain significance
rs535675469	13:92,006,309	T/C	—	uncertain significance
rs549650270	13:92,006,337	T/G	—	likely benign
rs955943126	13:92,006,822	T/C	—	likely benign
rs113352594	13:92,006,848	G/C	regulatory region variant	Benign

Gene information from NCBI Gene. Variant classifications from ClinVar.