MLIP
muscular LMNA interacting protein
Summary
Predicted to enable lamin binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of cardiac muscle hypertrophy in response to stress; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to be located in PML body; nuclear envelope; and sarcolemma. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants49 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2481550886 | 6:53,883,866 | A/G | — | likely benign |
| rs116512063 | 6:53,885,958 | T/C | upstream gene variant | — |
| rs7450517 | 6:53,902,843 | G/A | intron variant | — |
| rs9370258 | 6:53,910,988 | T/G | coding sequence variant | — |
| rs9382280 | 6:53,912,613 | C/T | upstream gene variant | — |
| rs9296736 | 6:53,924,697 | T/C | intron variant | — |
| rs7742515 | 6:53,942,185 | A/T | intron variant | — |
| rs589208 | 6:53,985,034 | T/C | — | — |
| rs150437140 | 6:53,989,347 | C/T | — | uncertain significance |
| rs374203719 | 6:53,989,362 | C/T | — | uncertain significance |
| rs1770745195 | 6:53,989,375 | A/C | — | uncertain significance |
| rs775570995 | 6:53,989,389 | C/A | — | uncertain significance |
| rs764062611 | 6:53,989,409 | C/A | — | uncertain significance |
| rs146387198 | 6:53,989,446 | T/C | — | uncertain significance |
| rs114749085 | 6:53,989,506 | G/C | — | uncertain significance |
| rs753459828 | 6:53,989,556 | A/T | — | uncertain significance |
| rs369010969 | 6:53,989,578 | G/A | — | uncertain significance |
| rs2481646954 | 6:53,989,638 | T/C | — | uncertain significance |
| rs2481647144 | 6:53,989,646 | C/T | — | pathogenic |
| rs749849105 | 6:53,989,658 | G/T | — | uncertain significance |
| rs765867577 | 6:53,989,659 | G/A | — | uncertain significance |
| rs631441 | 6:53,994,626 | T/C | — | — |
| rs816367 | 6:53,995,542 | G/C | intron variant | — |
| rs816372 | 6:53,997,693 | A/T | — | — |
| rs145626967 | 6:54,002,428 | A/G | — | uncertain significance |
| rs901032025 | 6:54,002,692 | A/T | — | pathogenic |
| rs142516820 | 6:54,003,052 | A/G | intron variant | — |
| rs816375 | 6:54,007,284 | G/A | intron variant | — |
| rs4715446 | 6:54,010,651 | A/T | intron variant | — |
| rs1366235422 | 6:54,013,857 | T/A | — | uncertain significance |
| rs200350443 | 6:54,013,873 | G/A | — | conflicting classifications of pathogenicity |
| rs1293901426 | 6:54,013,920 | C/T | — | pathogenic |
| rs1340661 | 6:54,023,382 | T/G | intron variant | — |
| rs142613357 | 6:54,025,173 | T/A | — | uncertain significance |
| rs2481944191 | 6:54,025,184 | A/G | — | uncertain significance |
| rs78446650 | 6:54,025,539 | A/G | — | benign |
| rs141526731 | 6:54,025,545 | C/G | — | benign |
| rs539057828 | 6:54,034,356 | C/T | — | pathogenic |
| rs6934690 | 6:54,054,686 | A/T | — | benign |
| rs35722245 | 6:54,054,699 | C/G | — | uncertain significance |
| rs777377431 | 6:54,054,713 | G/A | — | likely pathogenic |
| rs138048655 | 6:54,066,921 | C/T | — | uncertain significance |
| rs778331086 | 6:54,066,933 | G/A | — | uncertain significance |
| rs759649011 | 6:54,067,014 | G/A | — | uncertain significance |
| rs201710075 | 6:54,095,543 | T/C | — | uncertain significance |
| rs753759104 | 6:54,095,601 | G/C | — | uncertain significance |
| rs145131028 | 6:54,095,704 | G/A | — | uncertain significance |
| rs1342831 | 6:54,096,151 | T/C | intron variant | — |
| rs187896418 | 6:54,109,962 | G/A | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.