MUC17
mucin 17, cell surface associated
Summary
The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
Known Variants385 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs137964241 | 7:100,663,465 | T/A | — | uncertain significance |
| rs745526150 | 7:100,663,478 | C/G | — | uncertain significance |
| rs2485862727 | 7:100,674,890 | G/A | — | uncertain significance |
| rs751488304 | 7:100,674,912 | C/A | — | uncertain significance |
| rs774457079 | 7:100,674,969 | T/C | — | uncertain significance |
| rs146605853 | 7:100,674,993 | C/T | — | uncertain significance |
| rs753499828 | 7:100,675,004 | C/T | — | likely benign |
| rs2485863126 | 7:100,675,014 | C/G | — | uncertain significance |
| rs567129894 | 7:100,675,136 | G/A | — | likely benign |
| rs111227419 | 7:100,675,164 | G/A | — | uncertain significance |
| rs974330215 | 7:100,675,199 | C/G | — | uncertain significance |
| rs754012525 | 7:100,675,270 | T/A | — | likely benign |
| rs371729341 | 7:100,675,325 | A/G | — | uncertain significance |
| rs540080829 | 7:100,675,419 | T/C | — | uncertain significance |
| rs371532269 | 7:100,675,491 | T/G | — | uncertain significance |
| rs150719489 | 7:100,675,538 | C/A | — | likely benign |
| rs187460352 | 7:100,675,631 | G/A | — | uncertain significance |
| rs761589035 | 7:100,675,698 | C/T | — | uncertain significance |
| rs550020068 | 7:100,675,724 | A/C | — | uncertain significance |
| rs368047713 | 7:100,675,732 | G/A | — | likely benign |
| rs201681377 | 7:100,675,758 | T/A | — | uncertain significance |
| rs144713284 | 7:100,675,817 | C/T | — | uncertain significance |
| rs1035472931 | 7:100,675,845 | T/A | — | uncertain significance |
| rs1262522039 | 7:100,675,851 | C/A | — | uncertain significance |
| rs368614637 | 7:100,675,891 | G/A | — | uncertain significance |
| rs1358864412 | 7:100,675,904 | A/T | — | uncertain significance |
| rs1028604408 | 7:100,675,909 | G/T | — | uncertain significance |
| rs954265037 | 7:100,675,930 | C/G | — | uncertain significance |
| rs145279256 | 7:100,675,940 | A/G | — | likely benign |
| rs758742736 | 7:100,676,000 | A/G | — | uncertain significance |
| rs766914024 | 7:100,676,001 | C/A | — | uncertain significance |
| rs113525079 | 7:100,676,037 | C/T | — | uncertain significance |
| rs771488253 | 7:100,676,046 | G/C | — | uncertain significance |
| rs1562804217 | 7:100,676,084 | C/T | — | uncertain significance |
| rs756124682 | 7:100,676,106 | G/C | — | likely benign |
| rs764213479 | 7:100,676,150 | A/G | — | uncertain significance |
| rs550300233 | 7:100,676,157 | C/G | — | likely benign |
| rs2485869459 | 7:100,676,203 | A/G | — | likely benign |
| rs1189164936 | 7:100,676,245 | G/A | — | uncertain significance |
| rs763015879 | 7:100,676,343 | G/C | — | uncertain significance |
| rs752643628 | 7:100,676,422 | G/A | — | uncertain significance |
| rs764748549 | 7:100,676,493 | C/T | — | uncertain significance |
| rs750107408 | 7:100,676,501 | A/G | — | uncertain significance |
| rs757295422 | 7:100,676,540 | G/C | — | uncertain significance |
| rs766165527 | 7:100,676,608 | C/T | — | likely benign |
| rs756457667 | 7:100,676,618 | G/C | — | uncertain significance |
| rs375959111 | 7:100,676,633 | G/T | — | uncertain significance |
| rs2485872482 | 7:100,676,741 | A/G | — | uncertain significance |
| rs538801500 | 7:100,676,757 | G/A | — | uncertain significance |
| rs374584694 | 7:100,676,774 | A/G | — | uncertain significance |
| rs572058292 | 7:100,676,798 | G/T | — | uncertain significance |
| rs2485873067 | 7:100,676,832 | C/T | — | uncertain significance |
| rs1198550232 | 7:100,676,841 | C/A | — | uncertain significance |
| rs764876002 | 7:100,676,898 | G/A | — | uncertain significance |
| rs762011699 | 7:100,676,954 | C/A | — | uncertain significance |
| rs1157048264 | 7:100,677,043 | T/C | — | likely benign |
| rs370889038 | 7:100,677,085 | G/T | — | uncertain significance |
| rs557250612 | 7:100,677,113 | C/T | — | uncertain significance |
| rs373676381 | 7:100,677,131 | C/A | — | uncertain significance |
| rs771842676 | 7:100,677,147 | C/T | — | uncertain significance |
| rs2485875360 | 7:100,677,164 | G/A | — | uncertain significance |
| rs985943064 | 7:100,677,200 | A/C | — | uncertain significance |
| rs565675815 | 7:100,677,204 | C/T | — | uncertain significance |
| rs140905069 | 7:100,677,255 | C/T | — | uncertain significance |
| rs2485875968 | 7:100,677,261 | T/C | — | uncertain significance |
| rs761122407 | 7:100,677,275 | T/C | — | uncertain significance |
| rs151141256 | 7:100,677,284 | G/C | — | uncertain significance |
| rs536611151 | 7:100,677,289 | A/C | — | likely benign |
| rs558829231 | 7:100,677,293 | C/A | — | uncertain significance |
| rs541267676 | 7:100,677,302 | A/G | — | uncertain significance |
| rs559883624 | 7:100,677,305 | A/G | — | uncertain significance |
| rs1294113865 | 7:100,677,323 | C/G | — | uncertain significance |
| rs780718717 | 7:100,677,576 | A/G | — | uncertain significance |
| rs749105825 | 7:100,677,602 | G/A | — | uncertain significance |
| rs771891031 | 7:100,677,608 | A/G | — | uncertain significance |
| rs775116009 | 7:100,677,621 | C/A | — | uncertain significance |
| rs144234230 | 7:100,677,641 | A/G | — | uncertain significance |
| rs559649161 | 7:100,677,838 | G/A | — | uncertain significance |
| rs759900251 | 7:100,677,887 | A/T | — | uncertain significance |
| rs749912126 | 7:100,677,899 | G/A | — | uncertain significance |
| rs201494892 | 7:100,677,981 | C/T | — | uncertain significance |
| rs200569400 | 7:100,677,997 | C/A | — | uncertain significance |
| rs758817472 | 7:100,678,008 | C/A | — | uncertain significance |
| rs535755711 | 7:100,678,025 | A/T | — | uncertain significance |
| rs752339955 | 7:100,678,047 | A/G | — | uncertain significance |
| rs777596948 | 7:100,678,080 | C/G | — | uncertain significance |
| rs369901080 | 7:100,678,098 | C/G | — | uncertain significance |
| rs767983502 | 7:100,678,152 | C/A | — | uncertain significance |
| rs774621731 | 7:100,678,209 | T/C | — | likely benign |
| rs2485882413 | 7:100,678,368 | T/C | — | uncertain significance |
| rs10265276 | 7:100,678,421 | T/C | missense variant | — |
| rs145962817 | 7:100,678,510 | A/C | — | likely benign |
| rs73402889 | 7:100,678,527 | T/G | — | benign |
| rs755223781 | 7:100,678,565 | G/A | — | uncertain significance |
| rs2485884038 | 7:100,678,571 | A/G | — | uncertain significance |
| rs760397026 | 7:100,678,604 | G/C | — | uncertain significance |
| rs765576551 | 7:100,678,607 | G/A | — | uncertain significance |
| rs78010183 | 7:100,678,610 | A/T | missense variant | — |
| rs139014940 | 7:100,678,617 | G/T | — | uncertain significance |
| rs566973972 | 7:100,678,635 | A/G | — | uncertain significance |
Showing 100 of 385 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.