Trait
SNPs associated with Chronic Kidney Disease
83 genetic variants across 29 genes have been associated with Chronic Kidney Disease in published research. Key genes include AGT, APOL1, CCSER1.
Associated variants83 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs553908921 | CCSER1 | GWAS association (p=2.0e-08) | Meta-analysis |
| rs769354275 | CELF2 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs71785313 | APOL1 | Increased risk of CKD and kidney failure | Meta-analysis |
| rs73885319 | APOL1 | Increased risk of chronic kidney disease | Meta-analysis |
| rs699 | AGT | Altered chronic kidney disease susceptibility | Meta-analysis |
| rs77924615 | — | GWAS association (p=3.0e-107) | Major Consortium Study |
| rs9622362 | APOL1 | GWAS association (p=2.0e-45) | Major Consortium Study |
| rs36060036 | UMOD | GWAS association (p=1.0e-29) | Major Consortium Study |
| rs58384577 | APOL1 | GWAS association (p=3.0e-26) | Major Consortium Study |
| rs60295735 | — | GWAS association (p=8.0e-26) | Major Consortium Study |
| rs7903146 | TCF7L2 | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs34872471 | TCF7L2 | GWAS association (p=4.0e-23) | Major Consortium Study |
| rs10767873 | LOC101928338 | GWAS association (p=3.0e-22) | Major Consortium Study |
| rs963837 | LINC02859 | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs11642015 | FTO | GWAS association (p=5.0e-21) | Major Consortium Study |
| rs3925584 | LOC101928338 | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs56139727 | TPPP | GWAS association (p=4.0e-19) | Major Consortium Study |
| rs17730281 | WDR72 | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs2486272 | GATM | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs11604568 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs1613559 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs2622821 | — | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs11099098 | LOC124900725 | GWAS association (p=7.0e-14) | Major Consortium Study |
| rs1433880 | — | GWAS association (p=7.0e-14) | Major Consortium Study |
| rs948493 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs3127579 | SLC22A2 | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs62048402 | FTO | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs399277 | TPPP | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs2943653 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs10846744 | SCARB1 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs4948524 | — | GWAS association (p=9.0e-12) | Major Consortium Study |
| rs9645418 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs117139471 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs28362063 | UMOD | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs28910285 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs2203452 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs9998017 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs7756836 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs56094641 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs10518733 | WDR72 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs145220387 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs334 | HBB | Increased chronic kidney disease and end-stage renal disease risk | Major Consortium Study |
| rs6464165 | PRKAG2 | GWAS association (p=3.0e-32) | Major Consortium Study |
| rs10224210 | — | GWAS association (p=1.0e-29) | Major Consortium Study |
| rs9622363 | APOL1 | GWAS association (p=9.0e-46) | Major Consortium Study |
| rs13329952 | UMOD | GWAS association (p=2.0e-25) | Large GWAS |
| rs73728279 | — | GWAS association (p=7.0e-24) | Large GWAS |
| rs2490391 | — | GWAS association (p=4.0e-17) | Large GWAS |
| rs28817415 | SHROOM3 | GWAS association (p=2.0e-16) | Large GWAS |
| rs1145077 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs7805747 | PRKAG2 | GWAS association (p=4.0e-12) | Large GWAS |
| rs12509595 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs13230625 | — | GWAS association (p=9.0e-13) | Large GWAS |
| rs3812036 | SLC34A1 | GWAS association (p=1.0e-12) | Large GWAS |
| rs8096658 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs12917707 | UMOD | GWAS association (p=2.0e-12) | Large GWAS |
| rs7123489 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs2467853 | SPATA5L1 | GWAS association (p=2.0e-11) | Large GWAS |
| rs1362800 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs80282103 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs12207180 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs11123169 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs4976646 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs16942751 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs187355703 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs4293393 | UMOD | GWAS association (p=4.0e-10) | Large GWAS |
| rs2411192 | MYO19 | GWAS association (p=4.0e-09) | Large GWAS |
| rs6420094 | SLC34A1 | GWAS association (p=4.0e-09) | Large GWAS |
| rs200982668 | COL6A5 | GWAS association (p=5.0e-09) | Large GWAS |
| rs7422339 | — | GWAS association (p=8.0e-09) | Large GWAS |
| rs2823139 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs61734696 | MARCHF1 | GWAS association (p=2.0e-08) | Large GWAS |
| rs78010183 | MUC17 | GWAS association (p=2.0e-08) | Large GWAS |
| rs565845029 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs868822 | LOC124901792 | GWAS association (p=3.0e-08) | Large GWAS |
| rs1047891 | CPS1 | GWAS association (p=3.0e-08) | Large GWAS |
| rs4972593 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs10906850 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs2039424 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs146639727 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs139537100 | MOB3C | GWAS association (p=5.0e-08) | Large GWAS |
| rs200787930 | PLCB2 | GWAS association (p=5.0e-08) | Large GWAS |
| rs6066043 | SLC13A3 | GWAS association (p=2.0e-09) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.