MYO16

myosin XVI

Summary

This gene encodes an unconventional myosin protein. The encoded protein has been proposed to act as a serine/threonine phosphatase-1 targeting or regulatory subunit. Studies in a rat cell line suggest that this protein may regulate cell cycle progression. A variant within this gene may be associated with susceptibility to schizophrenia and elevated expression of this gene has been observed in the frontal cortex of human schizophrenia patients. [provided by RefSeq, Mar 2017]

Known Variants224 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs9559369	13:109,223,933	A/G	intergenic variant	—
rs150949191	13:109,235,412	C/A	intergenic variant	—
rs7338021	13:109,246,708	C/T	upstream gene variant	—
rs75764673	13:109,267,466	A/C	—	—
rs72664949	13:109,280,508	A/G	intron variant	—
rs138343083	13:109,318,259	T/C	—	benign
rs1314072693	13:109,318,264	C/A	—	uncertain significance
rs1594190080	13:109,318,265	C/G	—	likely benign
rs2501993734	13:109,318,300	C/T	—	uncertain significance
rs764834954	13:109,318,309	T/C	—	uncertain significance
rs374275936	13:109,318,316	A/G	—	benign
rs117770145	13:109,318,370	G/A	—	benign
rs61745206	13:109,318,373	C/T	—	benign
rs771238697	13:109,318,432	C/T	—	uncertain significance
rs779520347	13:109,318,452	A/G	—	likely benign
rs7984522	13:109,347,659	T/A	—	—
rs771130006	13:109,365,001	G/T	—	likely benign
rs144721835	13:109,365,049	C/T	—	likely benign
rs111464054	13:109,365,050	G/A	—	uncertain significance
rs2502223727	13:109,379,789	G/T	—	uncertain significance
rs766497298	13:109,379,806	G/T	—	uncertain significance
rs141525847	13:109,379,843	A/G	—	uncertain significance
rs1301423220	13:109,379,857	G/A	—	uncertain significance
rs10492418	13:109,380,726	A/C	regulatory region variant	—
rs9521026	13:109,423,089	G/A	intron variant	—
rs2893329	13:109,425,906	T/A	—	—
rs764547007	13:109,438,013	A/G	—	uncertain significance
rs911973	13:109,438,084	T/A	—	benign
rs200186426	13:109,445,884	C/T	—	uncertain significance
rs537057276	13:109,445,885	G/T	—	uncertain significance
rs2138945751	13:109,445,908	A/G	—	uncertain significance
rs906273783	13:109,445,910	G/A	—	uncertain significance
rs1245436424	13:109,445,969	A/G	—	uncertain significance
rs202097676	13:109,445,976	A/C	—	likely benign
rs984300	13:109,455,835	G/T	—	—
rs9301323	13:109,459,020	A/G	—	benign
rs2501655236	13:109,459,100	T/C	—	uncertain significance
rs149704651	13:109,472,710	T/A	—	benign
rs41308564	13:109,472,733	A/G	—	benign
rs17393344	13:109,473,946	G/A	intron variant	—
rs141603684	13:109,475,516	C/T	—	benign
rs969227915	13:109,475,557	C/G	—	uncertain significance
rs61742194	13:109,475,600	C/T	—	benign
rs144509002	13:109,475,602	A/G	—	benign
rs141132835	13:109,475,609	C/T	—	likely benign
rs405397	13:109,475,610	G/A	—	benign
rs112705392	13:109,476,531	T/C	intron variant	—
rs145720245	13:109,491,871	G/A	intron variant	—
rs768067917	13:109,496,694	T/C	—	likely benign
rs766294311	13:109,496,798	T/C	—	likely benign
rs16973313	13:109,496,813	C/T	—	benign
rs754732474	13:109,496,827	A/G	—	uncertain significance
rs183521986	13:109,496,839	C/G	—	uncertain significance
rs78265045	13:109,496,848	A/G	—	benign
rs17485138	13:109,502,849	C/T	intron variant	—
rs117493931	13:109,507,785	T/C	—	benign
rs556011063	13:109,507,812	C/G	—	uncertain significance
rs757251609	13:109,507,817	C/T	—	likely benign
rs140445068	13:109,507,838	C/T	—	likely benign
rs770273862	13:109,507,846	A/G	—	uncertain significance
rs2501886262	13:109,507,861	T/A	—	uncertain significance
rs1266031119	13:109,507,878	C/T	—	uncertain significance
rs201263234	13:109,507,884	G/A	—	uncertain significance
rs814141	13:109,511,059	T/A	—	—
rs150440488	13:109,518,568	A/C	—	uncertain significance
rs9559428	13:109,518,578	T/C	—	benign
rs117665810	13:109,535,415	G/C	—	benign
rs1020843490	13:109,535,432	C/T	—	uncertain significance
rs747731481	13:109,535,444	G/A	—	uncertain significance
rs774060871	13:109,535,458	C/T	—	likely pathogenic
rs149581024	13:109,535,513	G/T	—	uncertain significance
rs369318472	13:109,535,526	C/T	—	benign
rs45507695	13:109,540,756	A/G	—	benign
rs139224149	13:109,540,790	G/A	—	likely benign
rs143342209	13:109,540,795	C/G	—	uncertain significance
rs147534854	13:109,540,804	A/G	—	likely benign
rs140379648	13:109,540,828	A/G	—	likely benign
rs76952704	13:109,550,367	A/G	—	likely benign
rs186356943	13:109,550,460	A/G	—	uncertain significance
rs150706800	13:109,550,468	A/G	—	likely benign
rs746199612	13:109,550,477	C/T	—	likely benign
rs775969040	13:109,550,480	A/G	—	likely benign
rs139105351	13:109,562,400	T/C	—	likely benign
rs61743216	13:109,562,437	A/C	—	benign
rs61739459	13:109,562,479	A/G	—	conflicting classifications of pathogenicity
rs2502112117	13:109,562,500	T/C	—	uncertain significance
rs767788561	13:109,610,080	G/A	—	likely benign
rs143534845	13:109,610,100	T/C	—	likely benign
rs199624828	13:109,613,928	C/G	—	uncertain significance
rs112439513	13:109,613,970	C/T	—	benign
rs1883586635	13:109,613,989	C/A	—	uncertain significance
rs374363969	13:109,617,136	T/C	—	uncertain significance
rs2501617438	13:109,617,143	T/G	—	likely benign
rs114315469	13:109,644,717	G/A	—	benign
rs559790497	13:109,661,288	A/G	—	uncertain significance
rs143200097	13:109,661,307	C/T	—	likely benign
rs1310923933	13:109,661,338	A/C	—	uncertain significance
rs767295227	13:109,661,354	A/G	—	uncertain significance
rs3825491	13:109,661,359	C/G	—	benign
rs2501867050	13:109,672,100	A/C	—	uncertain significance

Showing 100 of 224 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.