MYO1C

myosin IC

Summary

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]

Known Variants237 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1153816217:1,368,823G/A—benign
rs7447736217:1,368,911C/T—benign
rs721200817:1,369,078G/A—benign
rs7397622117:1,369,090C/T—benign
rs7644664017:1,369,133T/C—benign
rs11261461917:1,369,338C/T—benign
rs3408612217:1,369,366G/A—benign
rs11134066117:1,370,255T/C—benign
rs230245917:1,370,459T/C—benign
rs230245817:1,370,542C/A—benign
rs13959921417:1,370,551G/A—likely benign
rs75072930717:1,370,579G/A—uncertain significance
rs77519816517:1,370,629C/T—likely benign
rs230245717:1,370,720T/C—benign
rs4562473417:1,370,739T/C—benign
rs4548469517:1,370,743G/A—likely benign
rs11806888617:1,370,753C/T—benign
rs36846431717:1,370,779C/G—uncertain significance
rs37544602117:1,370,802C/T—uncertain significance
rs11421434017:1,370,845G/A—likely benign
rs11508306317:1,370,923C/A—benign
rs806905917:1,371,088T/C—benign
rs14153879117:1,371,098A/G—benign
rs807285917:1,371,123T/C—benign
rs14228363217:1,371,161A/G—benign
rs18166844117:1,371,294C/T—likely benign
rs20136595017:1,371,322G/A—likely benign
rs13835045817:1,371,325C/T—likely benign
rs76451241917:1,371,336C/T—uncertain significance
rs54754583117:1,371,337G/A—likely benign
rs14783582717:1,371,342C/T—uncertain significance
rs76968996517:1,371,345T/C—uncertain significance
rs13798563317:1,371,361C/T—likely benign
rs4559833317:1,371,376T/C—likely benign
rs75118957817:1,371,389C/T—uncertain significance
rs1153816117:1,371,393C/T—benign
rs122372174117:1,371,413G/A—uncertain significance
rs807981117:1,371,473G/C—benign
rs11346710617:1,371,510C/T—likely benign
rs4550869917:1,371,536C/T—likely benign
rs1153815717:1,371,572T/C—uncertain significance
rs53387581817:1,371,581C/T—uncertain significance
rs806568517:1,371,752G/T—benign
rs37409148917:1,371,776G/A—likely benign
rs4554183917:1,371,808G/T—likely benign
rs4557593617:1,371,814G/A—benign
rs808038917:1,371,818C/T—benign
rs7839769517:1,371,929C/T—benign
rs228686917:1,371,975C/T—benign
rs228687017:1,371,996G/A—benign
rs806955217:1,372,008A/G—benign
rs806614717:1,372,035G/C—benign
rs1165620317:1,372,636G/A—benign
rs6175365517:1,372,839C/T—benign
rs6175365217:1,372,861T/G—likely benign
rs138882654517:1,372,893G/A—uncertain significance
rs750246617:1,372,970G/A—benign
rs930317517:1,372,987T/G—benign
rs5794611317:1,373,113G/A—benign
rs75787632717:1,373,507C/G—uncertain significance
rs136764074117:1,373,508C/T—likely benign
rs990510617:1,373,518T/C—benign
rs124959581717:1,373,526C/A—uncertain significance
rs7744549317:1,373,558G/A—benign
rs100231510817:1,373,567C/G—uncertain significance
rs207427229817:1,373,570G/C—uncertain significance
rs37769133917:1,373,580G/A—likely benign
rs75103714717:1,373,585C/T—uncertain significance
rs11668064317:1,373,586G/C—likely benign
rs37137996617:1,373,594G/A—uncertain significance
rs75954353317:1,373,597G/A—uncertain significance
rs5609130217:1,373,600C/T—benign
rs77594814917:1,373,601G/T—uncertain significance
rs19971092717:1,373,610G/A—likely benign
rs808137017:1,373,612T/C—benign
rs18663422717:1,373,636G/T—benign
rs56494803917:1,373,693T/C—likely benign
rs11526489117:1,373,709C/T—likely benign
rs207427744417:1,373,738G/T—uncertain significance
rs14060449317:1,373,742G/T—likely benign
rs54224453117:1,373,759T/C—uncertain significance
rs20077113717:1,373,868C/T—benign
rs14525812317:1,373,923T/A—uncertain significance
rs76276858417:1,373,944C/T—uncertain significance
rs15094860417:1,373,945G/A—likely benign
rs15103477317:1,374,045C/T—likely benign
rs230245517:1,374,195A/G—benign
rs139842187517:1,374,368G/C—uncertain significance
rs74782208017:1,374,376C/T—uncertain significance
rs15008243317:1,374,397T/C—uncertain significance
rs77742422917:1,374,451C/T—likely benign
rs5618887517:1,374,499G/A—benign
rs230245617:1,374,503C/T—benign
rs76013319517:1,374,582C/T—likely benign
rs4548219417:1,374,650C/G—benign
rs1245220017:1,374,849A/C—benign
rs7867247817:1,375,218G/A—likely benign
rs4553433317:1,375,354C/T—benign
rs127252551317:1,375,458G/A—uncertain significance
rs75272040717:1,375,462G/A—uncertain significance

Showing 100 of 237 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.