MYO7B

myosin VIIB

Summary

The protein encoded by this gene is found in brush border microvilli of epithelial cells in the intestines and kidneys. The encoded protein is involved in linking protocadherins to the actin cytoskeleton and is essential for proper microvilli function. This protein aids in the accumulation of intermicrovillar adhesion components such as harmonin and ANKS4B, and this accumulation is necessary for normal brush border action. [provided by RefSeq, Jan 2017]

Known Variants242 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs2468334508	2:128,321,765	A/G	—	uncertain significance
rs2468335041	2:128,321,816	T/C	—	uncertain significance
rs139876338	2:128,321,849	T/C	—	benign
rs200299859	2:128,322,821	G/A	—	likely benign
rs750122876	2:128,322,880	G/A	—	uncertain significance
rs765869041	2:128,322,889	C/T	—	uncertain significance
rs1161525455	2:128,322,898	G/A	—	uncertain significance
rs201898602	2:128,324,222	A/T	—	uncertain significance
rs1202483924	2:128,324,244	C/T	—	likely benign
rs145802059	2:128,324,271	C/G	—	benign
rs370941935	2:128,324,305	C/T	—	uncertain significance
rs115516718	2:128,324,328	G/A	—	benign
rs771875661	2:128,324,344	G/A	—	uncertain significance
rs117561134	2:128,324,358	C/T	—	benign
rs1483228419	2:128,324,395	A/G	—	uncertain significance
rs542130438	2:128,327,492	A/C	—	likely benign
rs577908289	2:128,331,506	G/T	—	uncertain significance
rs778889560	2:128,331,519	G/A	—	uncertain significance
rs763195684	2:128,331,554	G/A	—	uncertain significance
rs193069171	2:128,331,604	A/G	—	benign
rs758301128	2:128,331,632	C/T	—	uncertain significance
rs367806110	2:128,331,633	G/A	—	uncertain significance
rs185066623	2:128,331,644	C/G	—	benign
rs76746601	2:128,331,645	A/C	—	benign
rs2468404028	2:128,334,160	T/A	—	likely benign
rs1414285695	2:128,334,164	T/A	—	likely benign
rs757331346	2:128,334,176	G/C	—	uncertain significance
rs1281747586	2:128,334,181	G/T	—	uncertain significance
rs372906816	2:128,334,214	G/A	—	uncertain significance
rs192308013	2:128,335,763	G/A	—	uncertain significance
rs762467347	2:128,335,767	G/A	—	likely benign
rs549327895	2:128,335,798	G/A	—	uncertain significance
rs1157348404	2:128,335,810	G/A	—	likely benign
rs200261111	2:128,338,331	C/T	—	likely benign
rs377190422	2:128,338,332	G/A	—	uncertain significance
rs61738426	2:128,338,343	C/T	—	benign
rs775646954	2:128,338,359	G/A	—	uncertain significance
rs371259809	2:128,338,363	C/T	—	uncertain significance
rs200525792	2:128,338,380	G/A	—	uncertain significance
rs4662740	2:128,339,456	G/T	—	benign
rs773633676	2:128,339,512	T/C	—	uncertain significance
rs1189578714	2:128,339,546	C/G	—	uncertain significance
rs760253077	2:128,339,550	G/A	—	likely benign
rs781630446	2:128,339,574	G/T	—	uncertain significance
rs754223763	2:128,339,966	C/T	—	uncertain significance
rs532777565	2:128,340,016	C/A	—	uncertain significance
rs144080203	2:128,341,722	G/A	—	benign
rs746922996	2:128,341,785	C/T	—	uncertain significance
rs1398377869	2:128,341,786	G/A	—	uncertain significance
rs61742021	2:128,341,813	T/C	—	uncertain significance
rs1417991310	2:128,341,848	C/G	—	uncertain significance
rs777464321	2:128,341,897	G/A	—	uncertain significance
rs61743462	2:128,341,904	G/A	—	benign
rs373230646	2:128,342,389	G/C	—	uncertain significance
rs369143572	2:128,342,422	A/C	—	uncertain significance
rs10928773	2:128,345,960	T/C	—	benign
rs371153674	2:128,345,985	G/A	—	uncertain significance
rs373697450	2:128,345,989	C/T	—	likely benign
rs202039269	2:128,346,098	C/T	—	uncertain significance
rs374615055	2:128,346,099	G/A	—	uncertain significance
rs778294788	2:128,346,120	A/G	—	uncertain significance
rs1679393198	2:128,346,122	C/T	—	uncertain significance
rs763019482	2:128,347,685	C/T	—	uncertain significance
rs148645893	2:128,347,689	C/A	—	uncertain significance
rs61743282	2:128,347,710	T/C	—	likely benign
rs749183742	2:128,347,789	G/T	—	uncertain significance
rs376826480	2:128,350,374	C/A	—	uncertain significance
rs936305918	2:128,350,379	G/C	—	uncertain significance
rs370974785	2:128,350,410	G/A	—	likely benign
rs370029403	2:128,350,426	G/A	—	uncertain significance
rs540373240	2:128,350,431	C/G	—	uncertain significance
rs200327378	2:128,350,451	C/G	—	uncertain significance
rs115012061	2:128,350,464	G/T	—	benign
rs375115392	2:128,351,136	C/G	—	uncertain significance
rs2468498656	2:128,351,152	G/A	—	uncertain significance
rs892419585	2:128,351,154	A/G	—	uncertain significance
rs115592021	2:128,351,183	A/C	—	benign
rs13419716	2:128,351,504	C/T	regulatory region variant	—
rs898606427	2:128,354,068	G/T	—	uncertain significance
rs780212933	2:128,354,071	G/A	—	uncertain significance
rs781408782	2:128,354,087	A/G	—	likely benign
rs199683153	2:128,354,089	C/T	—	uncertain significance
rs561780781	2:128,354,116	G/A	—	uncertain significance
rs141776312	2:128,354,135	C/T	—	benign
rs200576326	2:128,363,428	C/G	—	uncertain significance
rs187068100	2:128,364,817	C/T	—	uncertain significance
rs377533883	2:128,364,818	G/A	—	uncertain significance
rs756017010	2:128,364,853	C/T	—	uncertain significance
rs199821381	2:128,364,873	G/A	—	likely benign
rs779875467	2:128,364,901	C/T	—	uncertain significance
rs1411735494	2:128,364,973	C/T	—	uncertain significance
rs370073682	2:128,366,304	G/A	—	uncertain significance
rs373870541	2:128,366,344	G/A	—	uncertain significance
rs138959423	2:128,366,363	C/T	—	benign
rs943673385	2:128,366,397	G/A	—	uncertain significance
rs1254826226	2:128,366,427	G/A	—	uncertain significance
rs370097871	2:128,366,441	G/A	—	likely benign
rs777432	2:128,367,092	G/A	—	benign
rs2468568569	2:128,367,096	A/G	—	uncertain significance
rs1680294245	2:128,367,120	C/G	—	uncertain significance

Showing 100 of 242 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.