NAAA
N-acylethanolamine acid amidase
Summary
Enables DNA-binding transcription factor binding activity and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including N-acylethanolamine metabolic process; N-acylphosphatidylethanolamine metabolic process; and sphingosine metabolic process. Located in lysosome and membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants39 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs78105394 | 4:76,831,958 | A/G | downstream gene variant | — |
| rs755702245 | 4:76,836,098 | C/T | — | uncertain significance |
| rs78046578 | 4:76,836,362 | T/C | intron variant | — |
| rs111330011 | 4:76,838,040 | T/C | intron variant | — |
| rs61664656 | 4:76,838,807 | C/T | intron variant | — |
| rs751253908 | 4:76,839,936 | A/G | — | uncertain significance |
| rs111427893 | 4:76,840,485 | A/G | intron variant | — |
| rs752935750 | 4:76,841,105 | T/C | — | uncertain significance |
| rs529142915 | 4:76,841,895 | G/A | — | uncertain significance |
| rs1297013204 | 4:76,841,922 | A/C | — | uncertain significance |
| rs2476096290 | 4:76,842,118 | A/T | — | uncertain significance |
| rs113751309 | 4:76,842,131 | A/T | — | uncertain significance |
| rs766395038 | 4:76,842,140 | G/A | — | uncertain significance |
| rs61736789 | 4:76,842,157 | C/T | — | benign |
| rs777433295 | 4:76,842,177 | G/A | — | uncertain significance |
| rs199640267 | 4:76,842,182 | G/C | — | uncertain significance |
| rs200426632 | 4:76,842,208 | A/T | — | uncertain significance |
| rs1247213456 | 4:76,842,222 | G/A | — | uncertain significance |
| rs116406284 | 4:76,842,283 | G/A | — | benign |
| rs10518142 | 4:76,842,874 | G/A | — | — |
| rs58317633 | 4:76,844,443 | T/A | — | — |
| rs368969473 | 4:76,846,891 | G/A | — | likely benign |
| rs577399544 | 4:76,846,959 | C/T | — | uncertain significance |
| rs9996608 | 4:76,848,231 | C/T | intron variant | — |
| rs72651379 | 4:76,848,954 | A/G | intron variant | — |
| rs758886611 | 4:76,852,424 | C/T | — | uncertain significance |
| rs560825914 | 4:76,854,827 | G/A | — | — |
| rs111981122 | 4:76,855,106 | A/C | intron variant | — |
| rs2476257604 | 4:76,857,274 | T/A | — | uncertain significance |
| rs199980319 | 4:76,861,233 | C/T | — | uncertain significance |
| rs187885550 | 4:76,861,244 | G/T | — | uncertain significance |
| rs192282293 | 4:76,861,285 | G/A | — | likely benign |
| rs200023694 | 4:76,861,304 | T/C | — | likely benign |
| rs930269177 | 4:76,861,308 | G/C | — | uncertain significance |
| rs770483833 | 4:76,861,931 | C/T | — | uncertain significance |
| rs765038362 | 4:76,861,989 | C/G | — | likely benign |
| rs1413137013 | 4:76,862,080 | G/A | — | uncertain significance |
| rs1228005993 | 4:76,862,086 | C/G | — | likely benign |
| rs184711956 | 4:76,862,747 | A/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.