rs78105394

This is a downstream gene variant variant in the NAAA gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

N-acylethanolamine-hydrolyzing acid amidase measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)

Allele G

OR 0.77

p 1.0e-41

N 3,301

Large GWAS

European

About NAAA

Enables DNA-binding transcription factor binding activity and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including N-acylethanolamine metabolic process; N-acylphosphatidylethanolamine metabolic process; and sphingosine metabolic process. Located in lysosome and membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all NAAA variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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