NCR1
natural cytotoxicity triggering receptor 1
Summary
Predicted to be involved in immune response-regulating signaling pathway. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants45 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs587713844 | 19:55,407,989 | C/T | — | — |
| rs58244710 | 19:55,408,195 | G/A | intergenic variant | — |
| rs57490427 | 19:55,408,391 | C/T | — | — |
| rs112878297 | 19:55,408,997 | G/A | intergenic variant | — |
| rs62124577 | 19:55,409,910 | T/C | intergenic variant | — |
| rs587712555 | 19:55,410,161 | A/G | — | — |
| rs140786877 | 19:55,413,309 | C/T | upstream gene variant | — |
| rs79478065 | 19:55,414,755 | T/C | — | — |
| rs4806621 | 19:55,417,469 | A/G | regulatory region variant | — |
| rs2515506515 | 19:55,417,555 | A/G | — | uncertain significance |
| rs778072493 | 19:55,417,898 | T/G | — | uncertain significance |
| rs758015528 | 19:55,417,937 | A/G | — | uncertain significance |
| rs587625915 | 19:55,417,991 | C/G | — | uncertain significance |
| rs2067633325 | 19:55,417,992 | A/G | — | uncertain significance |
| rs375177680 | 19:55,418,036 | G/C | — | uncertain significance |
| rs1569536504 | 19:55,418,073 | T/G | — | uncertain significance |
| rs777127236 | 19:55,418,081 | C/T | — | uncertain significance |
| rs1436743048 | 19:55,418,141 | A/G | — | likely benign |
| rs201331285 | 19:55,418,149 | G/A | — | likely benign |
| rs139123108 | 19:55,419,350 | T/A | intron variant | — |
| rs143981324 | 19:55,419,632 | T/C | regulatory region variant | — |
| rs8111853 | 19:55,420,234 | T/G | intron variant | — |
| rs779621907 | 19:55,420,690 | A/C | — | uncertain significance |
| rs1042065408 | 19:55,420,730 | C/T | — | uncertain significance |
| rs767326606 | 19:55,420,742 | A/G | — | uncertain significance |
| rs772041783 | 19:55,420,814 | G/A | — | uncertain significance |
| rs200970446 | 19:55,421,387 | A/G | — | likely benign |
| rs149458145 | 19:55,422,472 | C/T | intron variant | — |
| rs11084378 | 19:55,422,582 | G/A | intron variant | — |
| rs1253161777 | 19:55,424,097 | G/A | — | uncertain significance |
| rs752531481 | 19:55,424,126 | G/T | — | uncertain significance |
| rs775830 | 19:55,425,281 | T/C | downstream gene variant | — |
| rs184365818 | 19:55,427,822 | G/A | downstream gene variant | — |
| rs201572512 | 19:55,433,159 | A/G | — | — |
| rs622941 | 19:55,434,458 | G/C | downstream gene variant | — |
| rs4806623 | 19:55,435,639 | A/T | — | — |
| rs269949 | 19:55,441,769 | G/A | intron variant | — |
| rs104895503 | 19:55,441,939 | T/C | missense variant | pathogenic |
| rs541434750 | 19:55,443,634 | A/G | — | — |
| rs188552176 | 19:55,445,544 | C/T | intron variant | — |
| rs104895505 | 19:55,445,856 | C/T | splice region variant | pathogenic |
| rs104895502 | 19:55,449,463 | C/G | missense variant | pathogenic |
| rs104895506 | 19:55,449,464 | G/A | missense variant | pathogenic |
| rs104895554 | 19:55,449,511 | — | — | pathogenic |
| rs104895549 | 19:55,449,590 | G/A | missense variant | pathogenic |
Gene information from NCBI Gene. Variant classifications from ClinVar.