NLRC5

NLR family CARD domain containing 5

Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]

Known Variants191 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs199475959	16:57,022,561	G/A	—	not provided
rs199475960	16:57,022,572	G/A	—	not provided
rs199475961	16:57,022,839	C/G	—	not provided
rs199475962	16:57,023,117	C/T	—	not provided
rs199475963	16:57,023,152	G/A	—	not provided
rs199475964	16:57,023,377	C/G	—	not provided
rs289747	16:57,023,938	C/T	regulatory region variant	—
rs17290922	16:57,024,317	G/C	regulatory region variant	—
rs1566439	16:57,024,662	T/C	intron variant	—
rs289750	16:57,026,764	T/A	—	—
rs75378421	16:57,032,819	C/A	—	—
rs821465	16:57,036,358	C/T	—	—
rs176532	16:57,036,639	T/C	intron variant	—
rs16965039	16:57,047,299	T/C	coding sequence variant	—
rs199475965	16:57,054,456	T/C	—	not provided
rs2544357255	16:57,054,638	G/T	—	uncertain significance
rs773996257	16:57,054,692	A/C	—	uncertain significance
rs569522024	16:57,054,712	G/A	—	uncertain significance
rs777860818	16:57,054,740	C/T	—	likely benign
rs2544361024	16:57,054,750	T/G	—	uncertain significance
rs368996988	16:57,054,760	G/A	—	uncertain significance
rs772786249	16:57,054,779	A/G	—	uncertain significance
rs147394286	16:57,054,902	C/G	—	uncertain significance
rs185197208	16:57,055,635	G/A	intron variant	—
rs199475966	16:57,056,139	A/C	—	not provided
rs199475967	16:57,057,575	C/T	—	not provided
rs199475968	16:57,057,609	G/A	—	not provided
rs199475969	16:57,057,811	C/G	—	not provided
rs199475970	16:57,058,003	C/T	—	not provided
rs199475971	16:57,058,041	C/T	—	not provided
rs821470	16:57,058,582	A/C	—	—
rs148647729	16:57,059,318	G/A	—	uncertain significance
rs367809019	16:57,059,331	A/G	—	uncertain significance
rs779987156	16:57,059,337	G/A	—	uncertain significance
rs780366196	16:57,059,405	G/A	—	uncertain significance
rs750157089	16:57,059,450	G/A	—	uncertain significance
rs539891659	16:57,059,451	T/C	—	uncertain significance
rs2544481010	16:57,059,469	C/T	—	uncertain significance
rs2061202762	16:57,059,514	G/A	—	uncertain significance
rs144514123	16:57,059,517	C/T	—	uncertain significance
rs758446922	16:57,059,573	C/T	—	conflicting classifications of pathogenicity
rs777720142	16:57,059,574	G/A	—	uncertain significance
rs757860782	16:57,059,603	C/G	—	uncertain significance
rs199475972	16:57,059,702	A/G	—	not provided
rs1555520385	16:57,059,711	T/G	—	not provided
rs147147126	16:57,059,712	C/T	—	uncertain significance
rs770844231	16:57,059,733	A/G	—	uncertain significance
rs1341405132	16:57,059,989	C/G	—	uncertain significance
rs141391037	16:57,059,998	C/T	—	likely benign
rs199565452	16:57,060,009	C/T	—	likely benign
rs2544494443	16:57,060,020	G/A	—	uncertain significance
rs111881204	16:57,060,067	G/A	—	likely benign
rs778427595	16:57,060,125	G/A	—	uncertain significance
rs149735722	16:57,060,136	G/T	—	conflicting classifications of pathogenicity
rs376911783	16:57,060,158	A/G	—	likely benign
rs371278281	16:57,060,174	T/C	—	uncertain significance
rs1210008155	16:57,060,191	C/T	—	uncertain significance
rs1298795964	16:57,060,196	C/G	—	uncertain significance
rs201280147	16:57,060,200	C/G	—	uncertain significance
rs2061274875	16:57,060,275	A/G	—	uncertain significance
rs763777727	16:57,060,290	G/C	—	uncertain significance
rs1187695011	16:57,060,302	C/T	—	uncertain significance
rs753954614	16:57,060,446	A/C	—	likely benign
rs199912823	16:57,060,474	A/G	—	uncertain significance
rs199475974	16:57,060,480	C/A	—	not provided
rs147825465	16:57,060,598	G/A	—	likely benign
rs199475975	16:57,060,864	A/C	—	not provided
rs746931634	16:57,060,902	G/C	—	uncertain significance
rs199475976	16:57,061,043	A/G	—	not provided
rs199475977	16:57,061,084	T/C	—	not provided
rs199475978	16:57,061,955	C/T	—	not provided
rs756124181	16:57,062,009	G/A	—	uncertain significance
rs748383955	16:57,062,048	G/T	—	uncertain significance
rs770097845	16:57,062,237	C/A	—	uncertain significance
rs771824021	16:57,062,249	G/A	—	uncertain significance
rs202002811	16:57,063,711	A/G	—	uncertain significance
rs190627737	16:57,063,752	C/T	—	uncertain significance
rs375054548	16:57,063,753	G/A	—	uncertain significance
rs199779375	16:57,063,759	G/A	—	likely benign
rs755499346	16:57,063,956	G/A	—	uncertain significance
rs111233885	16:57,064,324	C/G	—	—
rs199475979	16:57,065,103	C/T	—	not provided
rs199475980	16:57,065,117	T/A	—	not provided
rs1308687171	16:57,065,326	C/T	—	uncertain significance
rs775155889	16:57,065,345	C/T	—	uncertain significance
rs2544622704	16:57,065,359	A/T	—	uncertain significance
rs199475981	16:57,065,409	T/C	—	not provided
rs199475982	16:57,065,430	C/G	—	not provided
rs35534915	16:57,067,536	G/A	—	likely benign
rs757264031	16:57,067,556	G/T	—	uncertain significance
rs749550111	16:57,067,576	G/A	—	likely benign
rs201051347	16:57,070,082	G/T	—	uncertain significance
rs189913085	16:57,070,259	C/T	intron variant	—
rs199475983	16:57,070,986	G/C	—	not provided
rs199475984	16:57,071,073	C/T	—	not provided
rs199475985	16:57,071,149	G/A	—	not provided
rs199850703	16:57,071,166	C/T	—	uncertain significance
rs137919442	16:57,071,167	G/A	—	benign
rs199475986	16:57,074,114	T/C	—	not provided
rs199475987	16:57,074,535	A/C	—	not provided

Showing 100 of 191 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.