NOA1
nitric oxide associated 1
Summary
The protein encoded by this gene is a nuclear-encoded GTPase that functions in the mitochondrion. Upon translation, this protein is imported into the nucleus and then into the nucleolus before being exported to the mitochondrion. The encoded protein is required for oxygen-dependent regulation of mitochondrial respiratory complexes and for mitochondrial protein synthesis. [provided by RefSeq, Dec 2015]
Known Variants53 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs373594983 | 4:57,829,651 | T/C | — | uncertain significance |
| rs2475888116 | 4:57,829,652 | G/A | — | likely benign |
| rs201263284 | 4:57,829,656 | A/G | — | uncertain significance |
| rs747111511 | 4:57,829,683 | T/C | — | uncertain significance |
| rs772947641 | 4:57,829,719 | T/A | — | uncertain significance |
| rs781282581 | 4:57,829,750 | C/T | — | uncertain significance |
| rs2475888474 | 4:57,829,766 | T/A | — | uncertain significance |
| rs778492742 | 4:57,830,589 | A/T | — | uncertain significance |
| rs1015009886 | 4:57,830,596 | C/G | — | uncertain significance |
| rs374897616 | 4:57,830,667 | A/G | — | uncertain significance |
| rs781753631 | 4:57,832,824 | C/T | — | likely benign |
| rs148340781 | 4:57,832,831 | C/T | — | likely benign |
| rs369847942 | 4:57,832,843 | G/C | — | likely benign |
| rs532216266 | 4:57,832,875 | C/T | — | uncertain significance |
| rs974523222 | 4:57,834,635 | G/A | — | uncertain significance |
| rs35514852 | 4:57,835,969 | C/T | intron variant | — |
| rs72627509 | 4:57,839,051 | C/G | upstream gene variant | — |
| rs57265257 | 4:57,839,280 | A/T | upstream gene variant | — |
| rs765464956 | 4:57,839,373 | G/C | — | likely benign |
| rs77797239 | 4:57,839,419 | A/G | — | benign |
| rs751186637 | 4:57,839,464 | A/T | — | uncertain significance |
| rs370816016 | 4:57,840,027 | C/T | — | uncertain significance |
| rs371038579 | 4:57,840,152 | T/C | — | uncertain significance |
| rs72606404 | 4:57,841,213 | G/A | — | — |
| rs1721924435 | 4:57,842,644 | C/T | — | uncertain significance |
| rs374594944 | 4:57,842,667 | T/G | — | uncertain significance |
| rs368739181 | 4:57,842,806 | T/C | — | uncertain significance |
| rs778665399 | 4:57,842,863 | C/G | — | likely benign |
| rs2475903395 | 4:57,842,874 | T/A | — | uncertain significance |
| rs148181499 | 4:57,842,895 | G/A | — | uncertain significance |
| rs778735675 | 4:57,842,929 | C/G | — | uncertain significance |
| rs200705421 | 4:57,842,943 | T/C | — | uncertain significance |
| rs201998848 | 4:57,842,977 | C/G | — | uncertain significance |
| rs533555143 | 4:57,843,058 | G/A | — | uncertain significance |
| rs997530444 | 4:57,843,076 | G/C | — | uncertain significance |
| rs1375872625 | 4:57,843,115 | C/G | — | uncertain significance |
| rs2475904425 | 4:57,843,147 | A/G | — | uncertain significance |
| rs777709287 | 4:57,843,167 | C/A | — | uncertain significance |
| rs564335995 | 4:57,843,175 | G/A | — | uncertain significance |
| rs1265407490 | 4:57,843,210 | C/G | — | uncertain significance |
| rs746921121 | 4:57,843,220 | C/G | — | uncertain significance |
| rs770738314 | 4:57,843,222 | G/C | — | uncertain significance |
| rs770384974 | 4:57,843,237 | C/T | — | uncertain significance |
| rs751811430 | 4:57,843,296 | G/T | — | uncertain significance |
| rs753827773 | 4:57,843,348 | G/C | — | uncertain significance |
| rs1318825053 | 4:57,843,382 | G/A | — | uncertain significance |
| rs2475905753 | 4:57,843,411 | T/G | — | uncertain significance |
| rs2475906446 | 4:57,843,528 | G/C | — | uncertain significance |
| rs377143671 | 4:57,843,548 | C/A | — | uncertain significance |
| rs1351210408 | 4:57,843,651 | C/T | — | uncertain significance |
| rs529554283 | 4:57,843,658 | G/C | — | uncertain significance |
| rs201957616 | 4:57,843,732 | G/T | — | benign |
| rs775630644 | 4:57,843,738 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.