NPAT

nuclear protein, coactivator of histone transcription

Summary

Enables transcription coactivator activity and transcription corepressor activity. Involved in cell cycle G1/S phase transition and positive regulation of transcription by RNA polymerase II. Located in Cajal body; Gemini of Cajal bodies; and cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants1,649 total

rsidPosition (GRCh37)AllelesClassClinVar
rs18322628311:108,028,578C/G—uncertain significance
rs55676514511:108,028,666T/C—likely benign
rs18793932111:108,028,730T/C—uncertain significance
rs213481373511:108,029,299G/A—uncertain significance
rs94247222711:108,029,321T/A—uncertain significance
rs75605348011:108,029,674C/T—uncertain significance
rs249668861111:108,029,678A/G—likely benign
rs55034784511:108,029,684C/T—likely benign
rs249668863411:108,029,687T/C—likely benign
rs76389397111:108,029,690T/G—uncertain significance
rs127407178111:108,029,695A/G—likely benign
rs249668867911:108,029,697A/C—uncertain significance
rs207782095711:108,029,700T/C—uncertain significance
rs117847770611:108,029,707C/T—uncertain significance
rs249668871811:108,029,710C/T—uncertain significance
rs213481434411:108,029,711C/T—uncertain significance
rs249668873011:108,029,722G/T—uncertain significance
rs145772309511:108,029,727G/A—uncertain significance
rs249668874611:108,029,728A/C—uncertain significance
rs77896799811:108,029,730C/G—uncertain significance
rs74613732811:108,029,731T/C—uncertain significance
rs249668877611:108,029,733G/C—uncertain significance
rs75850089611:108,029,734G/C—uncertain significance
rs37336983411:108,029,744T/C—uncertain significance
rs249668882811:108,029,746T/C—uncertain significance
rs129410956111:108,031,597T/G—likely benign
rs249669267011:108,031,610A/C—uncertain significance
rs76148660511:108,031,624T/C—uncertain significance
rs75869619611:108,031,627T/C—conflicting classifications of pathogenicity
rs148529580811:108,031,629G/C—uncertain significance
rs78022359411:108,031,630G/T—uncertain significance
rs37710478211:108,031,631T/C—uncertain significance
rs142907106611:108,031,634T/A—likely benign
rs138315788811:108,031,637T/C—likely benign
rs144299920011:108,031,638G/A—uncertain significance
rs249669281711:108,031,644G/C—uncertain significance
rs249669281911:108,031,645T/G—uncertain significance
rs249669282911:108,031,647A/C—uncertain significance
rs116578010811:108,031,649A/G—likely benign
rs249669284211:108,031,650T/G—uncertain significance
rs78152953811:108,031,656C/T—conflicting classifications of pathogenicity
rs18087571611:108,031,657T/G—uncertain significance
rs134265574111:108,031,659G/T—uncertain significance
rs77001613911:108,031,660A/T—uncertain significance
rs77811724511:108,031,665C/T—uncertain significance
rs74546784511:108,031,666G/A—uncertain significance
rs249669294311:108,031,667A/T—likely benign
rs249669302011:108,031,669A/C—uncertain significance
rs249669303011:108,031,670G/A—likely benign
rs135446468811:108,031,671T/C—uncertain significance
rs213481735411:108,031,673T/C—likely benign
rs249669305811:108,031,676C/G—uncertain significance
rs249669306411:108,031,678C/G—uncertain significance
rs249669307111:108,031,679A/G—likely benign
rs20076236511:108,031,680C/T—conflicting classifications of pathogenicity
rs37550738911:108,031,681G/A—uncertain significance
rs249669310711:108,031,685A/G—likely benign
rs249669312911:108,031,687C/A—uncertain significance
rs76825827411:108,031,690A/G—likely benign
rs131578477011:108,031,694C/T—likely benign
rs249669319611:108,031,702T/C—uncertain significance
rs249669320211:108,031,703C/T—likely benign
rs146523849211:108,031,705G/A—uncertain significance
rs249669323611:108,031,709T/C—likely benign
rs207784152911:108,031,712T/C—likely benign
rs119125555311:108,031,714T/C—uncertain significance
rs249669327911:108,031,716G/A—uncertain significance
rs124103594211:108,031,719C/G—uncertain significance
rs249669329411:108,031,720T/C—uncertain significance
rs36824307411:108,031,722C/G—uncertain significance
rs249669332911:108,031,725G/A—uncertain significance
rs125706861211:108,031,728G/C—uncertain significance
rs249669337011:108,031,734C/T—uncertain significance
rs75025445711:108,031,736A/C—uncertain significance
rs127937822311:108,031,738A/G—uncertain significance
rs37248154111:108,031,739C/A—uncertain significance
rs136562026911:108,031,742T/C—likely benign
rs249669341511:108,031,744G/T—uncertain significance
rs75186981511:108,031,746G/A—uncertain significance
rs249669343411:108,031,751A/C—uncertain significance
rs94003189911:108,031,752T/C—uncertain significance
rs249669345111:108,031,753C/G—uncertain significance
rs207784211311:108,031,759G/T—uncertain significance
rs207784214911:108,031,760A/C—likely benign
rs249669349211:108,031,762G/A—uncertain significance
rs249669350411:108,031,764G/A—uncertain significance
rs75496452611:108,031,765T/A—uncertain significance
rs105329043911:108,031,771A/G—uncertain significance
rs130381426211:108,031,773G/C—uncertain significance
rs75308018111:108,031,774T/A—uncertain significance
rs75666011711:108,031,776G/T—uncertain significance
rs249669355811:108,031,778C/G—uncertain significance
rs37551306711:108,031,780T/C—uncertain significance
rs249669357511:108,031,784A/C—uncertain significance
rs249669359611:108,031,791G/C—uncertain significance
rs126123484511:108,031,792C/T—uncertain significance
rs207784257011:108,031,796G/A—likely benign
rs132561598911:108,031,799G/C—likely benign
rs249669363111:108,031,800A/C—uncertain significance
rs249669363711:108,031,801G/C—uncertain significance

Showing 100 of 1,649 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.