OLA1
Obg like ATPase 1
Summary
This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has been observed in multiple types of cancer and may be associated with poor survival. Pseudogenes of this gene have been defined on chromosomes 17 and 22. [provided by RefSeq, Jun 2016]
Known Variants25 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1684715182 | 2:174,940,200 | A/G | — | uncertain significance |
| rs772015748 | 2:174,943,713 | A/T | — | uncertain significance |
| rs182055036 | 2:174,945,896 | C/T | — | uncertain significance |
| rs12466894 | 2:174,946,113 | G/A | — | — |
| rs764649077 | 2:174,946,655 | T/C | — | uncertain significance |
| rs2468417949 | 2:174,946,669 | T/G | — | uncertain significance |
| rs193920787 | 2:174,946,734 | A/C | — | uncertain significance |
| rs376243604 | 2:174,946,745 | A/G | — | uncertain significance |
| rs372491629 | 2:174,946,755 | G/A | — | uncertain significance |
| rs10173857 | 2:174,951,182 | C/T | intron variant | — |
| rs115330285 | 2:174,955,014 | G/T | — | — |
| rs78164392 | 2:174,960,260 | G/A | intron variant | — |
| rs151110191 | 2:174,988,345 | T/C | — | uncertain significance |
| rs2468478098 | 2:174,988,397 | T/G | — | uncertain significance |
| rs1686457506 | 2:175,006,620 | C/T | — | uncertain significance |
| rs1056989682 | 2:175,006,668 | A/G | — | uncertain significance |
| rs6433465 | 2:175,009,842 | C/G | intron variant | — |
| rs4972433 | 2:175,012,137 | G/T | — | — |
| rs16862488 | 2:175,086,153 | C/T | intron variant | — |
| rs200337544 | 2:175,087,768 | A/T | — | uncertain significance |
| rs2468128805 | 2:175,087,833 | G/A | — | uncertain significance |
| rs2468128807 | 2:175,087,835 | G/A | — | uncertain significance |
| rs2105455973 | 2:175,094,082 | G/A | — | uncertain significance |
| rs4425051 | 2:175,096,409 | A/C | — | — |
| rs557878124 | 2:175,111,506 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.