PALLD

palladin, cytoskeletal associated protein

Summary

This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Known Variants1,624 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs2710835	4:169,418,125	G/A	—	benign
rs540595354	4:169,418,249	G/C	—	benign
rs886059207	4:169,418,250	G/A	—	uncertain significance
rs777479051	4:169,418,256	C/A	—	uncertain significance
rs538959058	4:169,418,266	C/T	—	benign
rs2710836	4:169,418,267	A/T	—	benign
rs571957605	4:169,418,285	A/G	—	uncertain significance
rs886059208	4:169,418,289	G/T	—	uncertain significance
rs540285834	4:169,418,293	A/G	—	uncertain significance
rs189011214	4:169,418,313	C/G	—	uncertain significance
rs143268375	4:169,418,353	A/G	—	benign
rs150719521	4:169,418,354	G/A	—	uncertain significance
rs62333818	4:169,418,432	C/T	—	benign
rs75967573	4:169,432,294	T/C	—	benign
rs28415743	4:169,432,343	T/C	—	benign
rs372273201	4:169,432,648	G/A	—	likely benign
rs1460357554	4:169,432,661	A/G	—	likely benign
rs189385916	4:169,432,663	G/T	—	likely benign
rs2531426704	4:169,432,666	C/T	—	uncertain significance
rs936716881	4:169,432,667	C/T	—	likely benign
rs1332537876	4:169,432,669	C/A	—	uncertain significance
rs1561191306	4:169,432,670	C/G	—	likely benign
rs61051061	4:169,432,673	T/C	—	benign
rs1404559721	4:169,432,676	T/A	—	uncertain significance
rs2531426875	4:169,432,678	A/T	—	uncertain significance
rs2531426895	4:169,432,679	G/C	—	likely benign
rs774344207	4:169,432,682	C/G	—	likely benign
rs1339215037	4:169,432,692	T/C	—	uncertain significance
rs2531427111	4:169,432,693	C/A	—	uncertain significance
rs1404049802	4:169,432,703	C/A	—	uncertain significance
rs1415143769	4:169,432,704	A/C	—	uncertain significance
rs1407404681	4:169,432,705	T/C	—	uncertain significance
rs1762530827	4:169,432,706	G/T	—	uncertain significance
rs555178952	4:169,432,712	A/G	—	likely benign
rs1221889423	4:169,432,718	C/T	—	likely benign
rs201343910	4:169,432,720	A/G	—	conflicting classifications of pathogenicity
rs1441118500	4:169,432,722	A/G	—	uncertain significance
rs543156415	4:169,432,723	A/G	—	uncertain significance
rs765408388	4:169,432,724	T/C	—	likely benign
rs2531427544	4:169,432,730	C/T	—	likely benign
rs2531427573	4:169,432,733	C/T	—	likely benign
rs142076299	4:169,432,739	G/A	—	likely benign
rs1279884945	4:169,432,742	C/A	—	likely benign
rs2531427684	4:169,432,746	T/C	—	uncertain significance
rs751923889	4:169,432,750	C/G	—	uncertain significance
rs1180103507	4:169,432,760	C/T	—	likely benign
rs889514388	4:169,432,762	A/G	—	uncertain significance
rs2531427796	4:169,432,763	G/A	—	likely benign
rs1473022799	4:169,432,769	G/A	—	likely benign
rs375219239	4:169,432,771	T/A	—	uncertain significance
rs781680143	4:169,432,775	C/A	—	uncertain significance
rs753297099	4:169,432,777	A/T	—	uncertain significance
rs2531428001	4:169,432,784	T/C	—	likely benign
rs2531428033	4:169,432,786	A/T	—	uncertain significance
rs2531428100	4:169,432,790	G/A	—	likely benign
rs1380992269	4:169,432,792	C/T	—	uncertain significance
rs1402814517	4:169,432,793	C/T	—	likely benign
rs1409360651	4:169,432,794	C/T	—	uncertain significance
rs372582436	4:169,432,795	G/A	—	uncertain significance
rs2531428224	4:169,432,796	G/C	—	likely benign
rs995896228	4:169,432,798	G/C	—	uncertain significance
rs1402463175	4:169,432,800	G/A	—	uncertain significance
rs1356106356	4:169,432,801	C/T	—	uncertain significance
rs2531428305	4:169,432,802	C/T	—	likely benign
rs374875087	4:169,432,804	T/C	—	uncertain significance
rs1282194996	4:169,432,807	C/A	—	uncertain significance
rs2531428426	4:169,432,808	C/T	—	likely benign
rs539876255	4:169,432,809	G/C	—	uncertain significance
rs1224742641	4:169,432,813	C/T	—	uncertain significance
rs115481700	4:169,432,814	C/G	—	likely benign
rs559411263	4:169,432,818	A/G	—	uncertain significance
rs1554032915	4:169,432,819	C/A	—	uncertain significance
rs2531428629	4:169,432,821	G/C	—	uncertain significance
rs772090155	4:169,432,823	A/G	—	likely benign
rs775550730	4:169,432,824	G/T	—	uncertain significance
rs1266953093	4:169,432,827	T/A	—	uncertain significance
rs2531428790	4:169,432,831	A/C	—	uncertain significance
rs1762543146	4:169,432,833	T/G	—	uncertain significance
rs530034181	4:169,432,835	G/A	—	likely benign
rs2531428924	4:169,432,840	A/T	—	uncertain significance
rs1806729	4:169,432,841	G/A	—	benign
rs2531428994	4:169,432,844	G/A	—	likely benign
rs1292544454	4:169,432,846	T/C	—	uncertain significance
rs1302010200	4:169,432,848	T/G	—	uncertain significance
rs1391979108	4:169,432,849	C/T	—	uncertain significance
rs369178136	4:169,432,850	G/A	—	likely benign
rs767909709	4:169,432,855	T/C	—	uncertain significance
rs1762546180	4:169,432,856	T/A	—	likely benign
rs753135522	4:169,432,861	G/C	—	uncertain significance
rs2531429259	4:169,432,865	T/C	—	likely benign
rs2531429295	4:169,432,869	C/A	—	uncertain significance
rs756698993	4:169,432,870	C/T	—	uncertain significance
rs2531429335	4:169,432,871	T/G	—	likely benign
rs2531429381	4:169,432,873	C/A	—	uncertain significance
rs2531429408	4:169,432,874	A/C	—	likely benign
rs201038000	4:169,432,877	C/T	—	conflicting classifications of pathogenicity
rs373423877	4:169,432,878	C/A	—	uncertain significance
rs753395522	4:169,432,879	T/C	—	uncertain significance
rs2531429512	4:169,432,882	G/A	—	uncertain significance
rs376732578	4:169,432,884	G/C	—	conflicting classifications of pathogenicity

Showing 100 of 1,624 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.