PGLYRP3
peptidoglycan recognition protein 3
Summary
This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs138438992 | 1:153,270,461 | T/G | — | uncertain significance |
| rs2526550131 | 1:153,270,491 | G/C | — | uncertain significance |
| rs200719839 | 1:153,270,535 | G/A | — | uncertain significance |
| rs142436988 | 1:153,270,580 | G/A | — | benign |
| rs1156821222 | 1:153,270,601 | G/A | — | uncertain significance |
| rs1659523091 | 1:153,271,598 | A/C | — | uncertain significance |
| rs35460167 | 1:153,271,638 | A/G | — | benign |
| rs768738802 | 1:153,271,690 | T/A | — | uncertain significance |
| rs2526554204 | 1:153,271,696 | C/T | — | uncertain significance |
| rs762030999 | 1:153,271,705 | A/T | — | uncertain significance |
| rs768737213 | 1:153,274,894 | A/G | — | uncertain significance |
| rs779386007 | 1:153,274,909 | C/T | — | uncertain significance |
| rs897908935 | 1:153,274,950 | C/G | — | uncertain significance |
| rs1384888609 | 1:153,275,062 | C/T | — | uncertain significance |
| rs115222752 | 1:153,276,355 | T/C | — | benign |
| rs746868955 | 1:153,276,405 | T/C | — | uncertain significance |
| rs1447044770 | 1:153,276,435 | A/G | — | uncertain significance |
| rs143394889 | 1:153,277,443 | G/T | — | uncertain significance |
| rs150096890 | 1:153,277,452 | A/G | — | uncertain significance |
| rs529292918 | 1:153,277,714 | A/G | — | uncertain significance |
| rs76148921 | 1:153,279,549 | C/G | — | uncertain significance |
| rs377220685 | 1:153,279,566 | A/G | — | uncertain significance |
| rs577104401 | 1:153,279,585 | A/G | — | uncertain significance |
| rs745566623 | 1:153,279,593 | C/G | — | uncertain significance |
| rs74473220 | 1:153,279,597 | G/A | — | benign |
| rs762464930 | 1:153,279,604 | C/G | — | uncertain significance |
| rs200029112 | 1:153,279,608 | C/T | — | likely benign |
| rs116398429 | 1:153,279,664 | G/C | — | benign |
| rs779510247 | 1:153,279,710 | C/T | — | uncertain significance |
| rs552250352 | 1:153,279,713 | C/G | — | uncertain significance |
| rs41264634 | 1:153,283,078 | A/G | — | benign |
| rs200831497 | 1:153,283,092 | G/A | — | uncertain significance |
| rs755230803 | 1:153,283,108 | T/G | — | uncertain significance |
| rs2987763 | 1:153,286,034 | T/A | upstream gene variant | — |
| rs149979947 | 1:153,286,209 | G/A | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.