PIWIL4

piwi like RNA-mediated gene silencing 4

Summary

PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]

Known Variants59 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs1323466041	11:94,300,733	A/C	—	uncertain significance
rs753849450	11:94,301,938	A/G	—	uncertain significance
rs1948219005	11:94,308,218	G/A	—	uncertain significance
rs762967478	11:94,308,264	A/G	—	uncertain significance
rs568478354	11:94,310,582	G/T	—	uncertain significance
rs2496791922	11:94,310,605	G/A	—	uncertain significance
rs143080347	11:94,310,653	G/A	—	uncertain significance
rs2212361	11:94,312,323	T/C	intron variant	—
rs10831243	11:94,315,290	C/A	—	—
rs374149358	11:94,318,630	A/G	—	uncertain significance
rs148185887	11:94,318,637	A/G	—	uncertain significance
rs372125531	11:94,318,646	G/C	—	uncertain significance
rs903252968	11:94,318,655	A/G	—	uncertain significance
rs16920646	11:94,318,680	T/A	—	benign
rs10831245	11:94,319,888	G/A	intron variant	—
rs142289424	11:94,320,265	A/C	—	likely benign
rs753832490	11:94,320,293	A/G	—	uncertain significance
rs145516372	11:94,320,300	C/T	—	benign
rs200530015	11:94,320,305	G/A	—	likely benign
rs981394637	11:94,320,308	A/T	—	uncertain significance
rs758582024	11:94,322,287	A/T	—	uncertain significance
rs34492831	11:94,326,720	A/G	—	benign
rs762775635	11:94,328,561	C/T	—	uncertain significance
rs201952078	11:94,328,562	G/A	—	uncertain significance
rs781505518	11:94,328,580	A/G	—	uncertain significance
rs185746059	11:94,330,966	A/G	—	benign
rs1948576289	11:94,330,999	C/A	—	uncertain significance
rs145908122	11:94,331,007	C/A	—	uncertain significance
rs148131551	11:94,331,076	C/T	—	uncertain significance
rs146142445	11:94,334,972	G/A	—	likely benign
rs2496844814	11:94,334,979	G/A	—	uncertain significance
rs2496844816	11:94,334,980	C/G	—	uncertain significance
rs140141244	11:94,335,078	G/A	—	uncertain significance
rs76578146	11:94,335,094	G/T	—	likely benign
rs548080215	11:94,335,111	G/T	—	uncertain significance
rs769950349	11:94,337,186	A/C	—	uncertain significance
rs370900833	11:94,340,692	T/C	—	uncertain significance
rs781038818	11:94,340,704	C/T	—	uncertain significance
rs571078478	11:94,340,705	G/A	—	uncertain significance
rs116084295	11:94,340,728	A/G	—	benign
rs550503915	11:94,340,740	G/A	—	uncertain significance
rs371297833	11:94,340,776	G/A	—	uncertain significance
rs752535456	11:94,340,782	G/A	—	uncertain significance
rs749331631	11:94,340,794	G/C	—	uncertain significance
rs1303931706	11:94,341,762	T/C	—	uncertain significance
rs146415204	11:94,341,823	C/T	—	likely benign
rs140818509	11:94,349,659	G/A	—	likely benign
rs200109578	11:94,351,137	T/C	—	uncertain significance
rs1948864640	11:94,351,157	G/A	—	likely benign
rs149230455	11:94,352,943	T/C	—	uncertain significance
rs2496883667	11:94,352,979	C/A	—	uncertain significance
rs766849717	11:94,352,981	G/A	—	uncertain significance
rs750177185	11:94,353,009	C/A	—	uncertain significance
rs200987345	11:94,353,197	C/T	—	uncertain significance
rs2496884377	11:94,353,212	C/G	—	uncertain significance
rs1388559018	11:94,354,048	G/A	—	likely benign
rs781730867	11:94,354,114	A/C	—	uncertain significance
rs508485	11:94,354,479	C/T	3 prime UTR variant	—
rs533412	11:94,354,958	A/G	—	—

Gene information from NCBI Gene. Variant classifications from ClinVar.