rs508485
This is a 3 prime utr variant variant in the PIWIL4 gene.
▶Research that mentions this SNP (1)
▶Genetic variants in the metzincin metallopeptidase family genes predict melanoma survivalAssociationN=1,267Yinghui Xu et al.(2018)· Molecular Carcinogenesis
A two-stage association study of 1,267 melanoma patients identified 4 independent SNPs in metzincin metallopeptidase family genes predicting melanoma-specific survival: rs10090371 in MMP16 (HR=1.73, P=9.68E-05), rs788935 in ADAMTS3 (HR=1.46, P=0.002), rs10882807 in TLL2 (HR=1.68, P=3.32E-05), and rs3918251 in MMP9 (HR=0.67, P=0.003). Combined genetic variants improved survival prediction when added to clinical variables.
About PIWIL4
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]
View all PIWIL4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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