PLEKHO2
pleckstrin homology domain containing O2
Summary
Predicted to be involved in macrophage apoptotic process. Predicted to be located in extracellular region and ficolin-1-rich granule lumen. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants49 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs150929841 | 15:65,140,807 | G/A | — | uncertain significance |
| rs2506016490 | 15:65,140,813 | A/C | — | uncertain significance |
| rs575659681 | 15:65,140,931 | A/G | — | uncertain significance |
| rs147092751 | 15:65,140,937 | A/G | — | uncertain significance |
| rs200372603 | 15:65,147,116 | C/G | — | likely benign |
| rs774029981 | 15:65,147,133 | G/A | — | uncertain significance |
| rs199594189 | 15:65,147,149 | G/C | — | uncertain significance |
| rs753309928 | 15:65,147,160 | A/G | — | uncertain significance |
| rs1164448014 | 15:65,147,189 | C/T | — | uncertain significance |
| rs144415889 | 15:65,147,205 | G/A | — | uncertain significance |
| rs534659227 | 15:65,152,115 | C/G | — | uncertain significance |
| rs550556485 | 15:65,153,685 | G/A | — | uncertain significance |
| rs12595292 | 15:65,153,690 | G/A | synonymous variant | — |
| rs143331139 | 15:65,153,716 | G/A | missense variant | — |
| rs748867208 | 15:65,153,728 | G/T | — | uncertain significance |
| rs1328149412 | 15:65,157,106 | T/A | — | uncertain significance |
| rs753620849 | 15:65,157,128 | C/T | — | uncertain significance |
| rs2506025177 | 15:65,157,174 | C/A | — | uncertain significance |
| rs2506025192 | 15:65,157,194 | G/T | — | uncertain significance |
| rs1381108184 | 15:65,157,258 | C/T | — | uncertain significance |
| rs780814432 | 15:65,157,278 | G/A | — | uncertain significance |
| rs2084672306 | 15:65,157,336 | C/G | — | uncertain significance |
| rs199822327 | 15:65,157,407 | G/T | — | uncertain significance |
| rs372433168 | 15:65,157,483 | C/T | — | likely benign |
| rs774321420 | 15:65,157,486 | C/T | — | uncertain significance |
| rs149341153 | 15:65,157,529 | G/C | — | uncertain significance |
| rs758759909 | 15:65,157,537 | A/C | — | uncertain significance |
| rs892193576 | 15:65,157,540 | C/T | — | uncertain significance |
| rs1167564106 | 15:65,157,672 | C/T | — | uncertain significance |
| rs775967345 | 15:65,157,731 | A/G | — | uncertain significance |
| rs535807857 | 15:65,157,743 | C/T | — | uncertain significance |
| rs376816563 | 15:65,157,744 | C/G | — | uncertain significance |
| rs148450625 | 15:65,157,755 | C/G | — | uncertain significance |
| rs370063159 | 15:65,157,767 | C/G | — | uncertain significance |
| rs142633037 | 15:65,157,768 | A/T | — | uncertain significance |
| rs139634648 | 15:65,157,812 | C/T | — | uncertain significance |
| rs761257299 | 15:65,157,860 | G/C | — | uncertain significance |
| rs145121786 | 15:65,157,881 | A/G | — | uncertain significance |
| rs751300095 | 15:65,157,882 | C/T | — | uncertain significance |
| rs559616585 | 15:65,157,887 | A/G | — | uncertain significance |
| rs116174314 | 15:65,157,901 | G/C | — | uncertain significance |
| rs1206925210 | 15:65,157,920 | G/T | — | uncertain significance |
| rs769245876 | 15:65,157,921 | C/T | — | likely benign |
| rs376472778 | 15:65,157,935 | G/A | — | uncertain significance |
| rs183734056 | 15:65,157,939 | C/G | — | uncertain significance |
| rs143349495 | 15:65,157,948 | G/T | — | uncertain significance |
| rs2506026207 | 15:65,157,972 | A/C | — | uncertain significance |
| rs60128101 | 15:65,160,389 | T/A | — | — |
| rs59001897 | 15:65,160,392 | T/G | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.