rs60128101

This variant is located in the PLEKHO2 gene.

GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

angiopoietin-1 measurement

Allele A
OR 0.07
p 2.0e-20
N 47,745
Large GWAS
European

plasminogen activator inhibitor 1 measurement

Allele A
OR 0.06
p 6.0e-18
N 47,745
Large GWAS
European

platelet-derived growth factor subunit A measurement

Allele A
OR 0.06
p 6.0e-18
N 47,745
Large GWAS
European

level of amyloid-beta precursor protein in blood

Allele A
OR 0.06
p 2.0e-17
N 47,745
Large GWAS
European

C-C motif chemokine 13 level

Allele A
OR 0.05
p 2.0e-14
N 47,745
Large GWAS
European

platelet-derived growth factor subunit B level

Allele A
OR 0.05
p 3.0e-13
N 47,745
Large GWAS
European

proheparin-binding EGF-like growth factor level

Allele A
OR 0.05
p 1.0e-12
N 47,745
Large GWAS
European

level of platelet basic protein in blood

Allele A
OR 0.05
p 2.0e-12
N 47,745
Large GWAS
European

About PLEKHO2

Predicted to be involved in macrophage apoptotic process. Predicted to be located in extracellular region and ficolin-1-rich granule lumen. [provided by Alliance of Genome Resources, Jul 2025]

View all PLEKHO2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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