PLPPR1
phospholipid phosphatase related 1
Summary
This gene encodes a member of the plasticity-related gene (PRG) family. Members of the PRG family mediate lipid phosphate phosphatase activity in neurons and are known to be involved in neuronal plasticity. The protein encoded by this gene does not perform its function through enzymatic phospholipid degradation. This gene is strongly expressed in brain. It shows dynamic expression regulation during brain development and neuronal excitation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Known Variants19 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs147760462 | 9:103,796,996 | G/C | intron variant | — |
| rs2252504 | 9:103,798,614 | C/A | intron variant | — |
| rs2246594 | 9:103,819,890 | T/G | intron variant | — |
| rs1329080 | 9:103,924,236 | A/C | — | — |
| rs7849892 | 9:104,008,393 | G/T | — | — |
| rs561398374 | 9:104,024,774 | C/A | — | — |
| rs1239610230 | 9:104,032,282 | A/G | — | uncertain significance |
| rs201289914 | 9:104,048,416 | A/G | — | uncertain significance |
| rs761281978 | 9:104,048,506 | A/G | — | uncertain significance |
| rs764061295 | 9:104,071,619 | C/T | — | uncertain significance |
| rs1282708268 | 9:104,071,666 | G/A | — | uncertain significance |
| rs774975567 | 9:104,071,742 | C/T | — | uncertain significance |
| rs200667385 | 9:104,075,105 | C/T | — | uncertain significance |
| rs780787669 | 9:104,075,194 | C/T | — | uncertain significance |
| rs376477018 | 9:104,079,698 | C/T | — | uncertain significance |
| rs1045674628 | 9:104,079,712 | T/A | — | uncertain significance |
| rs140912404 | 9:104,086,317 | C/T | — | uncertain significance |
| rs772495204 | 9:104,086,322 | A/G | — | uncertain significance |
| rs776044397 | 9:104,086,325 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.