PLXNA2

plexin A2

Summary

This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]

Known Variants597 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs540998412	1:208,200,598	A/G	—	uncertain significance
rs146958450	1:208,200,640	C/T	—	uncertain significance
rs141651654	1:208,200,641	G/A	—	uncertain significance
rs778714938	1:208,200,646	C/T	—	uncertain significance
rs573661376	1:208,200,649	C/T	—	uncertain significance
rs201356824	1:208,200,655	T/A	—	uncertain significance
rs1571835947	1:208,200,659	C/T	—	uncertain significance
rs2526377928	1:208,200,662	C/G	—	uncertain significance
rs138665170	1:208,200,675	C/G	—	likely benign
rs762054923	1:208,200,677	C/T	—	uncertain significance
rs750030294	1:208,200,689	G/A	—	likely benign
rs2102293970	1:208,200,692	C/T	—	likely benign
rs775651275	1:208,201,341	G/T	—	likely benign
rs1664390198	1:208,201,351	C/T	—	likely benign
rs141837222	1:208,201,391	T/C	—	uncertain significance
rs1571836641	1:208,201,404	G/A	—	likely benign
rs1396033177	1:208,201,409	T/G	—	uncertain significance
rs139305640	1:208,201,419	C/T	—	uncertain significance
rs758935682	1:208,201,422	C/T	—	uncertain significance
rs140101798	1:208,201,423	G/A	—	likely benign
rs758243795	1:208,201,431	G/A	—	uncertain significance
rs970655950	1:208,201,439	T/C	—	uncertain significance
rs148742246	1:208,201,441	G/A	—	likely benign
rs750685623	1:208,201,443	C/T	—	uncertain significance
rs780393666	1:208,201,488	C/T	—	uncertain significance
rs370357486	1:208,201,497	C/T	—	uncertain significance
rs756463636	1:208,201,498	G/A	—	likely benign
rs373568235	1:208,201,524	C/T	—	likely benign
rs1280388664	1:208,202,171	T/C	—	uncertain significance
rs534398757	1:208,202,237	G/A	—	likely benign
rs577510815	1:208,202,246	C/T	—	likely benign
rs1571837680	1:208,202,249	C/A	—	likely benign
rs113155197	1:208,202,279	G/A	—	likely benign
rs1664420365	1:208,202,283	G/A	—	uncertain significance
rs778270546	1:208,202,307	G/T	—	uncertain significance
rs747471594	1:208,202,308	C/T	—	uncertain significance
rs144314864	1:208,202,309	G/A	—	likely benign
rs781351907	1:208,202,312	C/T	—	likely benign
rs201452499	1:208,202,342	G/A	—	likely benign
rs142549025	1:208,202,362	C/T	—	uncertain significance
rs752862705	1:208,202,370	C/A	—	uncertain significance
rs1664423599	1:208,202,384	G/T	—	likely benign
rs138753762	1:208,204,919	C/A	—	benign
rs199910807	1:208,204,925	G/C	—	likely benign
rs2526404108	1:208,204,955	C/T	—	likely benign
rs368772733	1:208,204,956	C/T	—	uncertain significance
rs767567094	1:208,204,970	A/G	—	likely benign
rs1664506273	1:208,204,981	G/T	—	uncertain significance
rs766991936	1:208,204,985	G/A	—	likely benign
rs2526404360	1:208,204,989	G/A	—	uncertain significance
rs754297836	1:208,205,000	T/C	—	likely benign
rs987573329	1:208,205,015	G/A	—	likely benign
rs146748679	1:208,205,023	T/C	—	uncertain significance
rs186740123	1:208,205,029	G/A	—	likely benign
rs781075633	1:208,205,039	G/A	—	likely benign
rs769539300	1:208,205,047	G/A	—	uncertain significance
rs56168065	1:208,205,054	A/G	—	likely benign
rs748345804	1:208,205,066	G/T	—	likely benign
rs760643170	1:208,205,080	C/T	—	uncertain significance
rs767094642	1:208,205,081	G/A	—	likely benign
rs201167422	1:208,205,114	G/A	—	likely benign
rs200141319	1:208,205,115	G/T	—	benign
rs1664511159	1:208,205,116	G/A	—	likely benign
rs376129373	1:208,205,121	G/C	—	likely benign
rs751123015	1:208,206,668	G/C	—	uncertain significance
rs944620565	1:208,206,679	C/T	—	likely benign
rs747157643	1:208,206,716	C/T	—	uncertain significance
rs2102303640	1:208,206,733	G/A	—	likely benign
rs141503079	1:208,206,738	C/T	—	uncertain significance
rs144221769	1:208,206,739	G/A	—	likely benign
rs763396411	1:208,206,755	A/G	—	uncertain significance
rs146570184	1:208,206,768	C/T	—	benign
rs761512286	1:208,206,787	G/A	—	likely benign
rs371608661	1:208,206,802	C/T	—	likely benign
rs749977479	1:208,206,803	G/A	—	uncertain significance
rs760158975	1:208,206,809	C/T	—	uncertain significance
rs1664570575	1:208,206,811	G/A	—	likely benign
rs1664570692	1:208,206,812	G/T	—	uncertain significance
rs377729868	1:208,206,815	C/T	—	uncertain significance
rs150555772	1:208,206,826	G/A	—	likely benign
rs1664571350	1:208,206,828	G/A	—	uncertain significance
rs149381114	1:208,206,835	C/T	—	likely benign
rs200628052	1:208,206,836	G/A	—	uncertain significance
rs1664572747	1:208,206,853	G/A	—	likely benign
rs78000533	1:208,206,868	G/A	—	likely benign
rs140375970	1:208,207,830	G/C	—	likely benign
rs2526420775	1:208,207,837	C/T	—	uncertain significance
rs3736963	1:208,207,839	G/A	—	benign
rs779368619	1:208,207,854	C/T	—	likely benign
rs748532278	1:208,207,855	G/A	—	uncertain significance
rs370850148	1:208,207,858	C/T	—	uncertain significance
rs770608043	1:208,207,859	G/A	—	uncertain significance
rs1664612447	1:208,207,893	G/A	—	likely benign
rs766591893	1:208,207,922	C/T	—	uncertain significance
rs141018338	1:208,207,923	C/T	—	benign
rs200900362	1:208,207,924	G/A	—	uncertain significance
rs151296962	1:208,207,929	G/T	—	uncertain significance
rs2526421830	1:208,207,947	G/A	—	likely benign
rs113008184	1:208,207,949	A/G	—	benign
rs201590466	1:208,211,703	C/T	—	likely benign

Showing 100 of 597 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.