rs758243795
This variant is located in the PLXNA2 gene.
▶ClinVar annotation
not provided; PLXNA2-related disorder
View on ClinVar →About PLXNA2
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]
View all PLXNA2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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