PLXNA4

plexin A4

Summary

Predicted to enable semaphorin receptor activity. Predicted to be involved in nervous system development; regulation of cell migration; and semaphorin-plexin signaling pathway. Predicted to act upstream of or within nervous system development; regulation of axon extension involved in axon guidance; and regulation of negative chemotaxis. Predicted to be located in membrane. Predicted to be part of semaphorin receptor complex. Predicted to be active in cerebellar climbing fiber to Purkinje cell synapse and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

Known Variants348 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs565182818	7:131,812,252	G/A	—	—
rs374306317	7:131,815,232	C/T	—	likely benign
rs199878062	7:131,815,233	G/A	—	likely benign
rs761156637	7:131,815,253	C/T	—	uncertain significance
rs756821201	7:131,815,274	T/G	—	likely benign
rs1296546484	7:131,815,287	A/C	—	uncertain significance
rs2671103	7:131,815,310	A/G	—	benign
rs201799383	7:131,815,312	C/T	—	uncertain significance
rs150228337	7:131,815,315	G/A	—	benign
rs193018515	7:131,815,337	C/T	—	likely benign
rs557348616	7:131,815,338	G/A	—	likely benign
rs10954361	7:131,815,343	G/A	regulatory region variant	benign
rs190064899	7:131,817,823	G/T	—	likely benign
rs200763664	7:131,817,833	G/A	—	likely benign
rs75848889	7:131,817,850	T/C	—	benign
rs753740431	7:131,817,858	T/C	—	uncertain significance
rs763670879	7:131,817,884	C/T	—	uncertain significance
rs201396021	7:131,817,907	G/A	—	likely benign
rs114567124	7:131,817,922	G/A	—	likely benign
rs779684650	7:131,825,433	C/T	—	uncertain significance
rs749115824	7:131,825,444	C/A	—	likely benign
rs374483138	7:131,825,492	G/A	—	likely benign
rs192307159	7:131,825,531	C/T	—	likely benign
rs371701043	7:131,825,574	C/T	—	likely benign
rs768447641	7:131,825,575	G/A	—	likely benign
rs1399090	7:131,829,128	C/A	—	—
rs1345661289	7:131,829,903	C/T	—	uncertain significance
rs180898561	7:131,829,904	G/A	—	likely benign
rs777575896	7:131,829,907	C/T	—	likely benign
rs148819176	7:131,830,052	A/G	—	benign
rs776632659	7:131,831,344	G/A	—	likely benign
rs1795440991	7:131,831,349	C/T	—	uncertain significance
rs370460371	7:131,831,350	G/A	—	likely benign
rs750385003	7:131,831,397	G/T	—	uncertain significance
rs778448954	7:131,831,421	G/A	—	uncertain significance
rs767411064	7:131,831,454	T/C	—	uncertain significance
rs200233123	7:131,832,704	C/T	—	uncertain significance
rs529500573	7:131,832,743	C/T	—	uncertain significance
rs372665539	7:131,832,744	G/A	—	likely benign
rs551122340	7:131,832,747	A/G	—	likely benign
rs745706919	7:131,833,317	T/C	—	likely benign
rs375808893	7:131,833,327	C/T	—	uncertain significance
rs369716462	7:131,833,329	C/T	—	likely benign
rs374139141	7:131,833,345	A/G	—	uncertain significance
rs150284097	7:131,833,390	C/T	—	uncertain significance
rs765386768	7:131,833,399	C/T	—	uncertain significance
rs777611144	7:131,844,259	G/A	—	uncertain significance
rs372771390	7:131,844,352	C/T	—	uncertain significance
rs377038963	7:131,844,353	G/A	—	likely benign
rs146283224	7:131,844,395	A/C	—	benign
rs113388134	7:131,848,893	A/G	—	benign
rs760866887	7:131,848,895	G/A	—	likely benign
rs140355078	7:131,848,904	G/T	—	benign
rs557551688	7:131,848,943	G/A	—	likely benign
rs762377518	7:131,848,964	G/A	—	likely benign
rs533523444	7:131,848,967	C/T	—	likely benign
rs376463343	7:131,848,976	G/A	—	likely benign
rs1412538771	7:131,849,953	C/T	—	likely benign
rs117985931	7:131,852,272	A/G	intron variant	—
rs751986751	7:131,853,053	G/A	—	likely benign
rs1168482740	7:131,853,071	C/G	—	likely benign
rs749584774	7:131,853,119	G/A	—	likely benign
rs73155258	7:131,853,148	C/T	—	likely benign
rs200917567	7:131,853,149	G/A	—	likely benign
rs369419660	7:131,853,173	G/A	—	likely benign
rs752343164	7:131,853,193	C/T	—	uncertain significance
rs118107843	7:131,853,205	C/T	—	uncertain significance
rs376632126	7:131,853,282	G/T	—	uncertain significance
rs200724235	7:131,853,284	G/A	—	likely benign
rs200800715	7:131,853,309	C/T	—	uncertain significance
rs201634564	7:131,853,318	C/T	—	uncertain significance
rs374466534	7:131,853,327	G/A	—	uncertain significance
rs12386622	7:131,853,601	G/A	intron variant	—
rs7341474	7:131,856,213	C/G	intron variant	—
rs1796405363	7:131,859,588	C/A	—	uncertain significance
rs201073381	7:131,859,624	G/A	—	likely benign
rs765580691	7:131,859,672	G/A	—	likely benign
rs13232207	7:131,859,678	G/T	splice region variant	benign
rs141129552	7:131,859,686	C/T	—	likely benign
rs540175711	7:131,859,687	G/A	—	likely benign
rs201296528	7:131,864,525	G/A	—	likely benign
rs758459805	7:131,864,526	C/T	—	uncertain significance
rs763668879	7:131,864,535	C/T	—	uncertain significance
rs374028222	7:131,864,560	C/T	—	uncertain significance
rs1005851874	7:131,864,575	G/T	—	uncertain significance
rs773306424	7:131,864,581	C/T	—	uncertain significance
rs202222743	7:131,864,582	G/A	—	likely benign
rs3734989	7:131,864,591	C/T	—	benign
rs761223020	7:131,864,593	C/T	—	uncertain significance
rs145089173	7:131,864,609	G/A	—	likely benign
rs748758866	7:131,864,615	G/A	—	likely benign
rs372461782	7:131,864,618	G/A	—	likely benign
rs561785917	7:131,864,627	G/T	—	likely benign
rs201499248	7:131,864,631	G/T	—	uncertain significance
rs374317794	7:131,864,657	G/A	—	likely benign
rs370836606	7:131,864,676	C/T	—	uncertain significance
rs139273933	7:131,865,105	A/G	intron variant	—
rs199519035	7:131,865,405	G/A	—	likely benign
rs144287352	7:131,865,417	C/T	—	likely benign
rs757878877	7:131,865,447	C/T	—	likely benign

Showing 100 of 348 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.