POU2AF1

POU class 2 homeobox associating factor 1

Summary

Enables transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants28 total

rsidPosition (GRCh37)AllelesClassClinVar
rs104275211:111,223,111A/Gdownstream gene variant—
rs1241755611:111,223,445G/Adownstream gene variant—
rs14083433711:111,225,020G/A—uncertain significance
rs76416580811:111,225,034A/C—uncertain significance
rs249662831511:111,225,110A/G—uncertain significance
rs76127957511:111,225,170G/A—uncertain significance
rs186080379511:111,225,210G/C—uncertain significance
rs147293707111:111,225,237G/T—uncertain significance
rs438738311:111,227,170T/C—benign
rs75253514611:111,228,342G/T—uncertain significance
rs159119054611:111,228,343T/G—uncertain significance
rs14787425111:111,228,370C/T—uncertain significance
rs249663995711:111,228,372G/A—uncertain significance
rs13987522511:111,228,401A/G—likely benign
rs14376946911:111,228,438G/A—benign
rs3566466711:111,228,529T/C—likely benign
rs76876408311:111,228,566G/A—likely benign
rs7300567611:111,229,101T/C——
rs1228208211:111,229,470T/C—benign
rs11622946511:111,229,531T/C—benign
rs3545469811:111,229,546G/A—benign
rs186094902711:111,229,623G/A—uncertain significance
rs1241963411:111,239,365G/Cintron variant—
rs3488046211:111,246,143G/T——
rs462230311:111,248,514C/G—benign
rs428301611:111,248,640G/A—benign
rs1121386311:111,249,785C/G—benign
rs1078982511:111,249,819A/G—benign

Gene information from NCBI Gene. Variant classifications from ClinVar.