PRR12

proline rich 12

Summary

This gene encodes a proline-rich protein that contains two A-T hook DNA binding domains. A chromosomal translocation and gene fusion between this gene and zinc finger, MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient. Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development. [provided by RefSeq, Jul 2016]

Known Variants380 total

rsidPosition (GRCh37)AllelesClassClinVar
rs212227445119:50,094,909T/G—likely benign
rs77692072919:50,094,976A/G—uncertain significance
rs1187856819:50,095,961T/Cregulatory region variant—
rs55499816219:50,096,680C/T—likely benign
rs115968941319:50,097,716T/A—uncertain significance
rs75664751319:50,097,731A/C—likely benign
rs7305804719:50,097,746G/A—likely benign
rs77179625019:50,097,747C/A—uncertain significance
rs37189695119:50,097,772C/T—likely benign
rs1041464319:50,097,784T/C—benign
rs127205933819:50,097,804G/T—uncertain significance
rs77973117419:50,097,810C/A—uncertain significance
rs251426925319:50,097,824T/C—uncertain significance
rs37160332919:50,097,826C/T—benign
rs251426926719:50,097,828C/T—uncertain significance
rs37519020819:50,097,853C/T—likely benign
rs129232347019:50,097,870C/T—uncertain significance
rs75708706119:50,097,976G/A—likely benign
rs146599548319:50,098,015C/T—likely benign
rs18783469019:50,098,072C/T—benign
rs251426959519:50,098,079C/T—uncertain significance
rs251426962119:50,098,097A/G—uncertain significance
rs76121078719:50,098,133G/A—uncertain significance
rs251426969919:50,098,169C/G—uncertain significance
rs55923626719:50,098,207C/T—likely benign
rs77612060119:50,098,225C/T—likely benign
rs37385653819:50,098,249C/T—likely benign
rs36758019819:50,098,250G/A—likely benign
rs14629170319:50,098,268C/T—likely benign
rs159978430419:50,098,270T/G—likely benign
rs76252773719:50,098,290A/G—uncertain significance
rs76645864419:50,098,301C/G—uncertain significance
rs89227081319:50,098,316C/T—uncertain significance
rs75955245619:50,098,366C/T—likely benign
rs76748734119:50,098,367G/A—likely benign
rs212228770919:50,098,377C/G—uncertain significance
rs208075698619:50,098,382C/T—pathogenic
rs75855355519:50,098,398C/T—uncertain significance
rs76644743819:50,098,399G/A—likely benign
rs1246275619:50,098,423G/A—benign
rs119038416519:50,098,427G/C—uncertain significance
rs208075793019:50,098,484G/A—uncertain significance
rs89242949819:50,098,495A/C—likely benign
rs251427027719:50,098,523C/T—pathogenic
rs251427028619:50,098,529T/C—uncertain significance
rs208075881919:50,098,590C/T—uncertain significance
rs810997419:50,098,592C/T—benign
rs208075892219:50,098,597T/A—uncertain significance
rs123011411419:50,098,606G/C—uncertain significance
rs208075919119:50,098,621T/C—likely benign
rs76156740719:50,098,649G/A—uncertain significance
rs54758378219:50,098,656C/T—likely benign
rs135271449719:50,098,664G/A—uncertain significance
rs122887924419:50,098,674G/A—uncertain significance
rs75266123719:50,098,686C/G—uncertain significance
rs76130200219:50,098,697G/T—uncertain significance
rs76469182419:50,098,702C/G—likely benign
rs37658081019:50,098,710C/T—likely benign
rs159978492619:50,098,720T/G—likely benign
rs20190822319:50,098,722G/T—likely benign
rs135939928319:50,098,727G/A—uncertain significance
rs77967635619:50,098,734G/A—uncertain significance
rs120129346419:50,098,739A/G—uncertain significance
rs208076112119:50,098,797G/T—uncertain significance
rs251427072819:50,098,805A/G—uncertain significance
rs76474471819:50,098,809C/A—uncertain significance
rs91034164519:50,098,814C/G—uncertain significance
rs55815232019:50,098,815C/T—likely benign
rs212228986919:50,098,817C/G—uncertain significance
rs212228990019:50,098,822T/G—likely benign
rs90128885919:50,098,823T/C—uncertain significance
rs134892241719:50,098,824C/A—likely pathogenic
rs57673807819:50,098,867C/T—likely benign
rs74717789919:50,098,886G/T—uncertain significance
rs76566286219:50,098,907G/A—likely benign
rs75371423819:50,098,935C/G—likely benign
rs140366755619:50,098,937C/T—likely pathogenic
rs37376840019:50,098,980G/C—likely benign
rs251427108719:50,099,012A/G—uncertain significance
rs208076353619:50,099,033C/T—pathogenic
rs251427114019:50,099,034A/C—uncertain significance
rs75022585019:50,099,036C/A—uncertain significance
rs137740195419:50,099,042A/C—uncertain significance
rs116048605819:50,099,066G/C—uncertain significance
rs251427125019:50,099,099C/T—pathogenic
rs11476178719:50,099,103G/C—likely benign
rs118674072319:50,099,113T/G—pathogenic
rs122119438319:50,099,123G/A—uncertain significance
rs20034038019:50,099,198G/A—likely benign
rs36815812519:50,099,200C/G—benign
rs54758792019:50,099,208C/T—uncertain significance
rs74739180319:50,099,211C/T—likely benign
rs14303574019:50,099,218G/A—benign
rs76304417919:50,099,223A/G—uncertain significance
rs53365670619:50,099,249C/G—uncertain significance
rs37281965219:50,099,260C/T—likely benign
rs75896725819:50,099,288C/G—uncertain significance
rs74877655419:50,099,329A/G—likely benign
rs14616798619:50,099,359C/T—benign
rs251427160119:50,099,364G/A—uncertain significance

Showing 100 of 380 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.