PSMA4
proteasome 20S subunit alpha 4
Summary
This gene encodes a core alpha subunit of the 20S proteosome, which is a highly ordered ring-shaped structure composed of four rings of 28 non-identical subunits. Proteasomes cleave peptides in an ATP- and ubiquitin-dependent manner. [provided by RefSeq, Aug 2016]
Known Variants23 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs34664138 | 15:78,831,624 | T/C | — | — |
| rs34138960 | 15:78,831,668 | A/T | — | — |
| rs538697229 | 15:78,831,801 | G/T | — | — |
| rs35212593 | 15:78,831,826 | G/A | upstream gene variant | — |
| rs12901682 | 15:78,833,223 | A/T | — | — |
| rs59133824 | 15:78,833,450 | C/T | — | — |
| rs2542705661 | 15:78,836,600 | T/G | — | uncertain significance |
| rs77434238 | 15:78,836,726 | T/G | — | — |
| rs11551774 | 15:78,837,262 | A/G | — | benign |
| rs780675206 | 15:78,838,102 | G/A | — | uncertain significance |
| rs1190276180 | 15:78,838,983 | T/G | — | uncertain significance |
| rs573135732 | 15:78,841,007 | A/G | — | — |
| rs776115821 | 15:78,841,198 | T/C | — | uncertain significance |
| rs753323656 | 15:78,841,215 | A/C | — | uncertain significance |
| rs1171027406 | 15:78,841,224 | G/A | — | uncertain significance |
| rs1979907 | 15:78,842,239 | T/C | downstream gene variant | — |
| rs1979906 | 15:78,842,289 | C/G | — | — |
| rs1979905 | 15:78,842,374 | A/T | — | — |
| rs12907966 | 15:78,843,051 | C/T | downstream gene variant | — |
| rs880395 | 15:78,844,356 | A/C | — | — |
| rs905740 | 15:78,844,386 | T/C | downstream gene variant | — |
| rs7164030 | 15:78,844,661 | G/C | — | — |
| rs905739 | 15:78,845,110 | A/G | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.