RAB25
RAB25, member RAS oncogene family
Summary
The protein encoded by this gene is a member of the RAS superfamily of small GTPases. The encoded protein is involved in membrane trafficking and cell survival. This gene has been found to be a tumor suppressor and an oncogene, depending on the context. Two variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2015]
Known Variants19 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs34372695 | 1:156,030,037 | C/T | downstream gene variant | — |
| rs2527703609 | 1:156,031,196 | G/A | — | uncertain significance |
| rs576937749 | 1:156,031,210 | G/A | — | uncertain significance |
| rs761473327 | 1:156,031,217 | A/G | — | uncertain significance |
| rs61751627 | 1:156,035,717 | A/G | — | likely benign |
| rs748885436 | 1:156,035,764 | G/A | — | uncertain significance |
| rs376965808 | 1:156,035,810 | C/T | — | uncertain significance |
| rs778900657 | 1:156,035,813 | G/A | — | uncertain significance |
| rs199867968 | 1:156,035,882 | G/A | — | uncertain significance |
| rs761125126 | 1:156,035,894 | C/G | — | uncertain significance |
| rs200399301 | 1:156,038,093 | T/G | — | uncertain significance |
| rs201936940 | 1:156,038,171 | C/T | — | uncertain significance |
| rs371998982 | 1:156,038,219 | G/A | — | uncertain significance |
| rs1647815028 | 1:156,038,239 | G/T | — | uncertain significance |
| rs368834458 | 1:156,039,479 | T/C | — | uncertain significance |
| rs777973695 | 1:156,039,529 | G/C | — | uncertain significance |
| rs115837676 | 1:156,039,960 | C/A | — | uncertain significance |
| rs947331634 | 1:156,039,972 | A/G | — | uncertain significance |
| rs199691333 | 1:156,039,980 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.