RAPGEFL1
Rap guanine nucleotide exchange factor like 1
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants25 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs74964489 | 17:38,331,495 | T/G | downstream gene variant | — |
| rs765143011 | 17:38,340,509 | C/T | — | uncertain significance |
| rs1330182244 | 17:38,340,905 | C/A | — | uncertain significance |
| rs864622033 | 17:38,345,135 | A/G | — | uncertain significance |
| rs2544390577 | 17:38,345,141 | C/T | — | uncertain significance |
| rs375362393 | 17:38,345,179 | C/T | — | uncertain significance |
| rs117771322 | 17:38,345,570 | G/C | — | uncertain significance |
| rs577984093 | 17:38,345,572 | G/T | — | uncertain significance |
| rs145951307 | 17:38,345,579 | G/A | — | uncertain significance |
| rs1307626928 | 17:38,345,580 | C/T | — | uncertain significance |
| rs143295458 | 17:38,345,585 | C/T | — | uncertain significance |
| rs779396839 | 17:38,346,713 | A/G | — | uncertain significance |
| rs1272785478 | 17:38,346,943 | C/T | — | uncertain significance |
| rs2544395189 | 17:38,346,956 | A/G | — | uncertain significance |
| rs1990233584 | 17:38,347,010 | A/C | — | uncertain significance |
| rs2145221766 | 17:38,347,011 | T/G | — | uncertain significance |
| rs1484278434 | 17:38,347,710 | C/T | — | uncertain significance |
| rs1990273485 | 17:38,347,847 | C/G | — | uncertain significance |
| rs2544398451 | 17:38,347,853 | C/G | — | uncertain significance |
| rs377071134 | 17:38,347,895 | G/A | — | uncertain significance |
| rs1304037046 | 17:38,349,642 | A/G | — | likely benign |
| rs2544403254 | 17:38,349,667 | T/G | — | uncertain significance |
| rs749240931 | 17:38,349,940 | A/G | — | uncertain significance |
| rs2544404287 | 17:38,349,985 | A/G | — | uncertain significance |
| rs45443194 | 17:38,352,255 | G/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.