RASGEF1A
RasGEF domain family member 1A
Summary
Enables guanyl-nucleotide exchange factor activity. Involved in cell migration and positive regulation of Ras protein signal transduction. Predicted to be located in cytosol. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants22 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2538783681 | 10:43,693,509 | G/C | — | uncertain significance |
| rs138913845 | 10:43,693,520 | C/T | — | uncertain significance |
| rs763163434 | 10:43,693,544 | C/T | — | uncertain significance |
| rs917832003 | 10:43,693,555 | C/G | — | uncertain significance |
| rs2435373 | 10:43,693,727 | G/T | — | — |
| rs1197489535 | 10:43,694,625 | G/T | — | uncertain significance |
| rs2538787509 | 10:43,695,671 | T/A | — | uncertain significance |
| rs2538788358 | 10:43,696,126 | G/C | — | uncertain significance |
| rs569429774 | 10:43,696,165 | C/T | — | uncertain significance |
| rs144394346 | 10:43,696,200 | G/C | — | uncertain significance |
| rs78581676 | 10:43,696,225 | C/T | — | uncertain significance |
| rs374420086 | 10:43,697,276 | G/A | — | uncertain significance |
| rs771491443 | 10:43,697,363 | C/T | — | uncertain significance |
| rs756884884 | 10:43,701,386 | G/A | — | uncertain significance |
| rs1304815523 | 10:43,701,435 | G/A | — | uncertain significance |
| rs764801376 | 10:43,701,477 | C/T | — | uncertain significance |
| rs781155802 | 10:43,701,501 | G/C | — | uncertain significance |
| rs375885001 | 10:43,701,513 | C/T | — | uncertain significance |
| rs184420302 | 10:43,716,041 | G/A | intron variant | — |
| rs2505547 | 10:43,732,336 | G/A | intron variant | — |
| rs2503855 | 10:43,738,332 | C/A | — | — |
| rs28461806 | 10:43,755,754 | T/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.