rs28461806

This variant is located in the RASGEF1A gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

C-C motif chemokine 2 level

Comuzzie AG et al. “Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.” Plos One 7(12):e51954 (2012)

Allele G

OR —

β 0.050

p 5.0e-8

N 1,078

Large GWAS

Hispanic or Latin American

About RASGEF1A

Enables guanyl-nucleotide exchange factor activity. Involved in cell migration and positive regulation of Ras protein signal transduction. Predicted to be located in cytosol. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all RASGEF1A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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