RBL2
RB transcriptional corepressor like 2
Summary
Enables promoter-specific chromatin binding activity. Involved in regulation of lipid kinase activity. Acts upstream of or within negative regulation of gene expression. Located in chromosome; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants82 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs34472536 | 16:53,468,491 | C/T | — | uncertain significance |
| rs2057936814 | 16:53,468,559 | G/A | — | uncertain significance |
| rs375627186 | 16:53,468,568 | G/T | — | uncertain significance |
| rs751668106 | 16:53,468,610 | C/T | — | uncertain significance |
| rs79388287 | 16:53,468,630 | C/T | — | benign |
| rs4146344 | 16:53,468,962 | C/T | regulatory region variant | — |
| rs1074182 | 16:53,471,357 | T/G | intron variant | — |
| rs372989712 | 16:53,472,934 | G/A | — | uncertain significance |
| rs377114480 | 16:53,472,937 | C/T | — | uncertain significance |
| rs778314573 | 16:53,472,938 | T/A | — | uncertain significance |
| rs755673624 | 16:53,472,955 | G/A | — | uncertain significance |
| rs2044685946 | 16:53,472,964 | G/A | — | uncertain significance |
| rs2057987326 | 16:53,472,988 | A/G | — | uncertain significance |
| rs149552198 | 16:53,473,033 | A/G | — | uncertain significance |
| rs72801818 | 16:53,476,042 | C/G | — | — |
| rs147880565 | 16:53,476,621 | A/G | — | benign |
| rs764676232 | 16:53,476,640 | C/T | — | uncertain significance |
| rs757262320 | 16:53,476,683 | T/A | — | uncertain significance |
| rs2153138545 | 16:53,476,754 | C/T | — | likely pathogenic |
| rs767827710 | 16:53,476,760 | A/G | — | uncertain significance |
| rs2058068934 | 16:53,480,955 | C/T | — | pathogenic |
| rs16952251 | 16:53,483,138 | A/G | coding sequence variant | — |
| rs1454341915 | 16:53,487,496 | C/G | — | uncertain significance |
| rs561811580 | 16:53,487,501 | A/G | — | uncertain significance |
| rs765703305 | 16:53,488,608 | G/A | — | uncertain significance |
| rs2506663371 | 16:53,488,626 | C/T | — | uncertain significance |
| rs765818967 | 16:53,488,648 | C/T | — | uncertain significance |
| rs72801832 | 16:53,491,171 | T/C | intron variant | — |
| rs1167825537 | 16:53,493,364 | C/T | — | uncertain significance |
| rs1361957467 | 16:53,493,424 | C/T | — | uncertain significance |
| rs149055093 | 16:53,493,435 | C/T | — | uncertain significance |
| rs2058199723 | 16:53,493,444 | A/C | — | uncertain significance |
| rs780116712 | 16:53,493,451 | C/T | — | uncertain significance |
| rs773048850 | 16:53,495,679 | C/T | — | uncertain significance |
| rs61747628 | 16:53,495,681 | A/G | — | likely benign |
| rs377229110 | 16:53,495,731 | G/T | — | uncertain significance |
| rs756677584 | 16:53,496,491 | C/T | — | uncertain significance |
| rs150610062 | 16:53,496,526 | A/G | — | uncertain significance |
| rs769694024 | 16:53,496,548 | T/G | — | uncertain significance |
| rs370604468 | 16:53,498,141 | A/G | — | uncertain significance |
| rs140896175 | 16:53,498,223 | A/T | — | benign |
| rs772227281 | 16:53,498,246 | T/C | — | uncertain significance |
| rs8054299 | 16:53,498,655 | C/A | — | — |
| rs144371880 | 16:53,499,365 | A/G | — | uncertain significance |
| rs148475258 | 16:53,499,418 | T/G | — | uncertain significance |
| rs1315218699 | 16:53,501,001 | A/G | — | uncertain significance |
| rs553666067 | 16:53,501,054 | C/T | — | uncertain significance |
| rs4783812 | 16:53,503,110 | C/G | intron variant | — |
| rs766382060 | 16:53,503,947 | C/T | — | uncertain significance |
| rs753074399 | 16:53,503,977 | G/A | — | uncertain significance |
| rs202227701 | 16:53,504,026 | A/G | — | uncertain significance |
| rs777659313 | 16:53,504,349 | G/C | — | uncertain significance |
| rs377369435 | 16:53,504,385 | C/T | — | uncertain significance |
| rs374414587 | 16:53,504,418 | G/A | — | uncertain significance |
| rs138343701 | 16:53,504,511 | A/C | — | uncertain significance |
| rs61747629 | 16:53,504,536 | A/T | — | benign |
| rs148298620 | 16:53,504,547 | C/T | — | uncertain significance |
| rs144971281 | 16:53,504,687 | G/A | — | likely benign |
| rs61759888 | 16:53,504,707 | A/G | — | uncertain significance |
| rs10748 | 16:53,504,721 | T/C | synonymous variant | — |
| rs72801843 | 16:53,508,802 | T/A | intron variant | — |
| rs1197922937 | 16:53,513,081 | A/G | — | uncertain significance |
| rs149956581 | 16:53,513,096 | A/G | — | uncertain significance |
| rs373573938 | 16:53,513,129 | C/T | — | uncertain significance |
| rs61759889 | 16:53,513,807 | A/C | — | uncertain significance |
| rs1366435098 | 16:53,514,517 | A/C | — | uncertain significance |
| rs1297492448 | 16:53,514,527 | T/C | — | uncertain significance |
| rs369264709 | 16:53,514,545 | C/G | — | uncertain significance |
| rs199555150 | 16:53,514,580 | A/G | — | uncertain significance |
| rs1004456022 | 16:53,514,587 | T/C | — | uncertain significance |
| rs2543466382 | 16:53,514,600 | G/T | — | uncertain significance |
| rs201148402 | 16:53,514,630 | C/T | — | likely benign |
| rs1960911443 | 16:53,514,658 | G/A | — | uncertain significance |
| rs370255143 | 16:53,515,585 | G/T | — | uncertain significance |
| rs2094143960 | 16:53,515,586 | G/C | — | uncertain significance |
| rs1478258607 | 16:53,515,635 | G/A | — | uncertain significance |
| rs2543469853 | 16:53,515,683 | A/C | — | uncertain significance |
| rs758976804 | 16:53,515,715 | A/G | — | uncertain significance |
| rs72801853 | 16:53,516,824 | A/G | intron variant | — |
| rs879846607 | 16:53,524,102 | A/G | — | uncertain significance |
| rs2543493834 | 16:53,524,174 | C/T | — | uncertain significance |
| rs72801859 | 16:53,524,654 | C/G | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.