RNF141
ring finger protein 141
Summary
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis. [provided by RefSeq, Jul 2008]
Known Variants6 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs755704389 | 11:10,536,582 | G/A | — | uncertain significance |
| rs778944428 | 11:10,536,601 | G/C | — | uncertain significance |
| rs377333979 | 11:10,550,301 | T/C | — | — |
| rs771510261 | 11:10,552,296 | G/A | — | uncertain significance |
| rs189167758 | 11:10,552,705 | C/T | intron variant | — |
| rs1293238581 | 11:10,555,642 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.