SAFB2
scaffold attachment factor B2
Summary
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016]
Known Variants69 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs201263017 | 19:5,587,265 | G/A | — | uncertain significance |
| rs772716396 | 19:5,587,289 | G/C | — | uncertain significance |
| rs1379389992 | 19:5,587,319 | C/G | — | uncertain significance |
| rs200585644 | 19:5,587,340 | C/T | — | uncertain significance |
| rs148112097 | 19:5,587,408 | C/G | — | uncertain significance |
| rs565231015 | 19:5,587,713 | C/A | — | uncertain significance |
| rs771915355 | 19:5,587,737 | T/C | — | uncertain significance |
| rs2512190443 | 19:5,587,752 | A/C | — | uncertain significance |
| rs376399865 | 19:5,587,939 | G/A | — | uncertain significance |
| rs772496640 | 19:5,587,959 | C/T | — | uncertain significance |
| rs2052299386 | 19:5,587,977 | C/G | — | uncertain significance |
| rs764613505 | 19:5,587,983 | C/T | — | uncertain significance |
| rs140108933 | 19:5,590,344 | C/T | — | uncertain significance |
| rs1599223985 | 19:5,590,347 | C/G | — | uncertain significance |
| rs1475850594 | 19:5,590,349 | C/G | — | uncertain significance |
| rs376677397 | 19:5,590,359 | G/A | — | uncertain significance |
| rs371251193 | 19:5,590,363 | G/T | — | uncertain significance |
| rs374443575 | 19:5,590,376 | C/T | — | uncertain significance |
| rs565743190 | 19:5,590,377 | G/A | — | uncertain significance |
| rs1456806527 | 19:5,590,395 | G/C | — | uncertain significance |
| rs368641426 | 19:5,590,403 | C/T | — | uncertain significance |
| rs138330957 | 19:5,590,418 | T/A | — | uncertain significance |
| rs2512195310 | 19:5,591,766 | T/A | — | uncertain significance |
| rs529098214 | 19:5,591,797 | C/T | — | uncertain significance |
| rs750771193 | 19:5,592,788 | C/T | — | uncertain significance |
| rs763274968 | 19:5,592,828 | G/A | — | uncertain significance |
| rs767956745 | 19:5,592,839 | G/A | — | uncertain significance |
| rs139056681 | 19:5,592,866 | C/T | — | uncertain significance |
| rs201770103 | 19:5,592,884 | T/C | — | uncertain significance |
| rs1196956940 | 19:5,593,923 | C/T | — | uncertain significance |
| rs773955427 | 19:5,593,932 | C/T | — | uncertain significance |
| rs759936375 | 19:5,593,936 | G/A | — | uncertain significance |
| rs2052474654 | 19:5,593,941 | T/A | — | uncertain significance |
| rs761756340 | 19:5,593,955 | C/G | — | uncertain significance |
| rs756692498 | 19:5,593,993 | G/T | — | uncertain significance |
| rs1193414852 | 19:5,594,031 | C/T | — | uncertain significance |
| rs2512198912 | 19:5,594,062 | C/T | — | uncertain significance |
| rs548751633 | 19:5,594,065 | T/G | — | likely benign |
| rs1264807606 | 19:5,594,127 | G/A | — | uncertain significance |
| rs771115168 | 19:5,594,184 | C/T | — | uncertain significance |
| rs986210649 | 19:5,595,493 | C/T | — | uncertain significance |
| rs806703 | 19:5,598,458 | G/T | — | — |
| rs371519329 | 19:5,598,817 | C/G | — | uncertain significance |
| rs778514046 | 19:5,598,833 | C/T | — | uncertain significance |
| rs1178046731 | 19:5,604,662 | C/G | — | uncertain significance |
| rs142026681 | 19:5,604,862 | G/A | — | uncertain significance |
| rs193920906 | 19:5,604,877 | G/A | — | uncertain significance |
| rs774519315 | 19:5,604,922 | T/C | — | uncertain significance |
| rs779188321 | 19:5,610,082 | C/T | — | uncertain significance |
| rs200845160 | 19:5,610,676 | A/G | — | uncertain significance |
| rs371499049 | 19:5,613,477 | G/A | — | uncertain significance |
| rs768813457 | 19:5,613,486 | T/C | — | uncertain significance |
| rs762919983 | 19:5,613,490 | A/C | — | uncertain significance |
| rs571681336 | 19:5,615,081 | A/G | — | — |
| rs779603451 | 19:5,616,165 | G/A | — | uncertain significance |
| rs1410431615 | 19:5,616,216 | T/C | — | uncertain significance |
| rs779944871 | 19:5,616,217 | C/T | — | uncertain significance |
| rs772801577 | 19:5,616,253 | G/A | — | uncertain significance |
| rs145240132 | 19:5,616,260 | G/C | — | uncertain significance |
| rs778994244 | 19:5,616,313 | T/C | — | uncertain significance |
| rs140521200 | 19:5,616,319 | G/T | — | uncertain significance |
| rs200942241 | 19:5,616,342 | T/G | — | uncertain significance |
| rs745354607 | 19:5,616,458 | A/G | — | uncertain significance |
| rs2512228811 | 19:5,616,462 | C/T | — | uncertain significance |
| rs2512228833 | 19:5,616,473 | G/C | — | uncertain significance |
| rs1443463692 | 19:5,616,491 | T/A | — | uncertain significance |
| rs139305134 | 19:5,619,038 | G/C | upstream gene variant | — |
| rs753305309 | 19:5,621,367 | A/G | — | uncertain significance |
| rs374601886 | 19:5,622,716 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.