SCARF2

scavenger receptor class F member 2

Summary

The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Known Variants153 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs10212080	22:20,778,447	G/A	regulatory region variant	—
rs146628881	22:20,779,216	G/A	regulatory region variant	—
rs748750395	22:20,779,678	G/A	—	uncertain significance
rs367657189	22:20,779,687	C/T	—	uncertain significance
rs745943062	22:20,779,690	C/T	—	uncertain significance
rs769974381	22:20,779,691	C/T	—	uncertain significance
rs773092954	22:20,779,704	C/T	—	likely benign
rs1450230038	22:20,779,706	C/T	—	uncertain significance
rs371459064	22:20,779,708	T/C	—	uncertain significance
rs754436179	22:20,779,711	C/T	—	uncertain significance
rs1448828018	22:20,779,720	T/C	—	uncertain significance
rs758888141	22:20,779,728	C/T	—	likely benign
rs587777658	22:20,779,735	—	—	pathogenic
rs537247534	22:20,779,744	G/A	—	conflicting classifications of pathogenicity
rs778152234	22:20,779,753	C/T	—	uncertain significance
rs874101	22:20,779,768	C/G	—	benign
rs749349489	22:20,779,778	C/T	—	uncertain significance
rs874100	22:20,779,822	G/C	—	benign
rs768688238	22:20,779,829	C/T	—	uncertain significance
rs762266997	22:20,779,925	G/A	—	likely benign
rs1182875086	22:20,779,939	C/T	—	likely benign
rs1421018530	22:20,780,018	G/C	—	benign
rs762551525	22:20,780,076	C/T	—	likely benign
rs185252842	22:20,780,079	C/T	—	benign
rs1171701467	22:20,780,082	G/C	—	benign
rs755214686	22:20,780,090	C/T	—	uncertain significance
rs1317279643	22:20,780,184	G/T	—	uncertain significance
rs778525967	22:20,780,202	G/A	—	likely benign
rs746555186	22:20,780,227	C/T	—	uncertain significance
rs777257623	22:20,780,233	G/A	—	uncertain significance
rs148669220	22:20,780,237	C/G	—	uncertain significance
rs763225303	22:20,780,247	G/C	—	uncertain significance
rs751535844	22:20,780,255	C/T	—	uncertain significance
rs2517416848	22:20,780,281	G/C	—	uncertain significance
rs150746534	22:20,780,285	C/A	—	conflicting classifications of pathogenicity
rs752523166	22:20,780,293	G/C	—	uncertain significance
rs369044776	22:20,780,294	G/A	—	uncertain significance
rs9680797	22:20,780,296	A/G	—	likely benign
rs2517416939	22:20,780,327	A/G	—	uncertain significance
rs761786923	22:20,780,344	A/G	—	uncertain significance
rs984158225	22:20,780,356	G/A	—	conflicting classifications of pathogenicity
rs1212420883	22:20,780,366	G/A	—	uncertain significance
rs1475035263	22:20,780,383	G/A	—	uncertain significance
rs1490201334	22:20,780,386	A/C	—	uncertain significance
rs2517417224	22:20,780,396	A/G	—	uncertain significance
rs1040319582	22:20,780,411	G/A	—	uncertain significance
rs900419088	22:20,780,441	T/A	—	uncertain significance
rs2517417428	22:20,780,455	G/C	—	uncertain significance
rs2052575948	22:20,780,461	G/A	—	uncertain significance
rs1290926703	22:20,780,467	G/A	—	uncertain significance
rs201929223	22:20,780,474	C/T	—	benign
rs748444087	22:20,780,509	G/A	—	uncertain significance
rs772315504	22:20,780,522	C/G	—	uncertain significance
rs1453982319	22:20,780,524	G/A	—	likely benign
rs1307120079	22:20,780,533	G/C	—	uncertain significance
rs1005655055	22:20,780,550	C/T	—	likely benign
rs765096717	22:20,780,560	G/A	—	uncertain significance
rs2517417814	22:20,780,563	G/A	—	uncertain significance
rs775551765	22:20,780,564	G/A	—	uncertain significance
rs996846647	22:20,780,588	G/C	—	likely benign
rs12152201	22:20,781,371	T/C	—	benign
rs78563796	22:20,781,373	C/G	—	benign
rs77025632	22:20,781,445	A/G	—	benign
rs545863119	22:20,781,668	G/C	—	likely benign
rs57590287	22:20,781,670	T/C	—	benign
rs2052591458	22:20,781,698	A/C	—	uncertain significance
rs76472118	22:20,781,725	G/A	—	likely benign
rs150853613	22:20,781,732	G/A	—	benign
rs762904849	22:20,781,735	G/A	—	uncertain significance
rs2517419381	22:20,781,738	A/G	—	uncertain significance
rs779303835	22:20,781,769	G/A	—	uncertain significance
rs529975990	22:20,781,778	G/A	—	benign
rs747268559	22:20,781,783	G/A	—	uncertain significance
rs768570979	22:20,781,815	G/A	—	likely benign
rs774221546	22:20,781,816	T/C	—	uncertain significance
rs150565069	22:20,781,827	G/A	—	benign
rs75119577	22:20,782,084	G/A	—	likely benign
rs2241231	22:20,782,102	G/C	—	benign
rs116142926	22:20,782,139	G/C	—	benign
rs5997411	22:20,783,485	A/C	—	benign
rs759078205	22:20,783,535	C/T	—	uncertain significance
rs754706730	22:20,783,569	T/A	—	uncertain significance
rs986754872	22:20,783,574	C/T	—	uncertain significance
rs2517422194	22:20,783,604	T/G	—	uncertain significance
rs2517422197	22:20,783,605	T/C	—	uncertain significance
rs766711136	22:20,783,660	G/A	—	likely benign
rs199752737	22:20,783,692	G/C	—	likely benign
rs8137004	22:20,783,721	C/T	—	benign
rs372461021	22:20,783,829	G/T	—	uncertain significance
rs111838285	22:20,783,834	G/A	—	likely benign
rs758312309	22:20,783,947	G/A	—	likely benign
rs2517423473	22:20,784,002	C/T	—	likely benign
rs2517423495	22:20,784,019	A/C	—	uncertain significance
rs1221207571	22:20,784,023	G/A	—	uncertain significance
rs2241230	22:20,784,050	T/A	—	benign
rs882745	22:20,784,217	T/C	—	benign
rs7289390	22:20,784,550	A/G	—	benign
rs73156937	22:20,784,630	C/A	—	benign
rs371080622	22:20,784,698	C/T	—	likely benign
rs1439190464	22:20,784,699	G/A	—	likely benign

Showing 100 of 153 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.