SDK1

sidekick cell adhesion molecule 1

Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

Known Variants275 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs1262699193	7:3,341,226	G/C	—	uncertain significance
rs1256941432	7:3,341,234	C/T	—	uncertain significance
rs867967855	7:3,341,276	C/G	—	likely benign
rs868126478	7:3,341,304	G/A	—	uncertain significance
rs1779263157	7:3,341,310	C/T	—	uncertain significance
rs867965028	7:3,341,358	A/C	—	uncertain significance
rs868254792	7:3,341,360	C/A	—	uncertain significance
rs1291204042	7:3,341,373	G/C	—	uncertain significance
rs1464303887	7:3,341,385	A/C	—	uncertain significance
rs1459318762	7:3,341,386	G/T	—	uncertain significance
rs2128539379	7:3,341,387	A/C	—	uncertain significance
rs2128539405	7:3,341,400	A/C	—	uncertain significance
rs1029440073	7:3,341,420	T/G	—	uncertain significance
rs1779269740	7:3,341,424	G/T	—	uncertain significance
rs891076876	7:3,341,429	C/T	—	uncertain significance
rs1239634620	7:3,341,443	G/C	—	uncertain significance
rs1020658052	7:3,341,450	C/A	—	uncertain significance
rs542888434	7:3,341,461	C/G	—	likely benign
rs2128539497	7:3,341,472	C/T	—	uncertain significance
rs1183380347	7:3,341,481	C/G	—	uncertain significance
rs1047961283	7:3,341,505	C/T	—	uncertain significance
rs4588749	7:3,363,992	A/G	intron variant	—
rs7790430	7:3,432,943	G/C	intron variant	—
rs1915982	7:3,510,606	G/A	—	—
rs7780621	7:3,519,047	G/A	—	—
rs533794760	7:3,568,156	G/A	—	—
rs10264275	7:3,597,457	A/C	—	—
rs549417529	7:3,622,079	A/G	—	—
rs572678504	7:3,622,497	G/A	—	—
rs4257931	7:3,643,330	G/A	intron variant	—
rs570967973	7:3,658,777	C/T	—	uncertain significance
rs373250128	7:3,658,792	C/T	—	uncertain significance
rs1245646313	7:3,658,817	A/T	—	uncertain significance
rs373681739	7:3,658,828	A/G	—	uncertain significance
rs80073557	7:3,658,832	G/A	—	benign
rs959894	7:3,661,033	T/A	intron variant	—
rs142103239	7:3,669,237	C/G	—	—
rs74637827	7:3,669,616	A/G	intron variant	—
rs143792155	7:3,678,680	G/A	—	uncertain significance
rs1782563170	7:3,678,706	G/A	—	uncertain significance
rs984396570	7:3,681,593	T/C	—	uncertain significance
rs761000435	7:3,681,599	G/A	—	likely benign
rs78444417	7:3,681,615	C/G	—	benign
rs557845855	7:3,681,619	A/G	—	uncertain significance
rs373076145	7:3,681,626	C/T	—	uncertain significance
rs141367524	7:3,681,640	C/A	—	uncertain significance
rs377228621	7:3,681,641	G/A	—	likely benign
rs2534238804	7:3,681,664	C/T	—	uncertain significance
rs773707490	7:3,681,695	C/T	—	uncertain significance
rs1215591870	7:3,681,707	A/C	—	uncertain significance
rs1782669837	7:3,681,710	G/T	—	uncertain significance
rs200464210	7:3,681,714	C/A	—	uncertain significance
rs370417123	7:3,681,721	A/C	—	uncertain significance
rs117235846	7:3,701,703	C/G	—	—
rs6965119	7:3,723,267	C/T	intron variant	—
rs187543070	7:3,819,092	A/G	—	—
rs6975313	7:3,842,905	C/T	intron variant	—
rs771683947	7:3,861,137	G/A	—	uncertain significance
rs756773617	7:3,861,140	G/A	—	uncertain significance
rs145830129	7:3,861,149	G/A	—	uncertain significance
rs1191124053	7:3,861,210	T/C	—	uncertain significance
rs6462411	7:3,915,564	T/C	intron variant	—
rs548832768	7:3,923,631	G/A	—	—
rs10263496	7:3,925,999	T/G	intron variant	—
rs113952142	7:3,956,753	C/A	intron variant	—
rs117632561	7:3,990,565	C/T	—	benign
rs543392497	7:3,990,569	C/T	—	uncertain significance
rs147733079	7:3,990,590	A/G	—	uncertain significance
rs771758488	7:3,990,608	A/G	—	uncertain significance
rs371890587	7:3,990,615	G/A	—	uncertain significance
rs1191310306	7:3,990,630	C/T	—	uncertain significance
rs34775958	7:3,990,657	C/T	—	benign
rs142657541	7:3,991,465	G/A	—	uncertain significance
rs61745546	7:3,991,485	C/A	—	benign
rs761878251	7:3,991,489	G/A	—	uncertain significance
rs76259242	7:3,991,493	T/C	—	likely benign
rs752266363	7:3,991,526	G/A	—	uncertain significance
rs780195200	7:3,991,534	G/A	—	uncertain significance
rs1475154582	7:3,991,540	C/G	—	uncertain significance
rs74804675	7:3,991,560	G/A	—	benign
rs201173308	7:3,998,566	C/T	—	uncertain significance
rs61735677	7:3,998,588	C/T	—	benign
rs201896234	7:3,998,596	G/A	—	uncertain significance
rs752828919	7:3,998,604	G/C	—	uncertain significance
rs150503747	7:4,002,309	C/G	—	likely benign
rs202020244	7:4,002,355	G/A	—	uncertain significance
rs148919634	7:4,002,369	G/A	—	uncertain significance
rs555285055	7:4,002,391	A/C	—	uncertain significance
rs2533903118	7:4,002,405	G/C	—	uncertain significance
rs141891693	7:4,002,413	C/T	—	likely benign
rs1781803465	7:4,002,441	G/A	—	uncertain significance
rs368751556	7:4,002,442	A/T	—	uncertain significance
rs936538026	7:4,002,455	C/G	—	uncertain significance
rs1781805660	7:4,002,465	A/T	—	uncertain significance
rs138011826	7:4,002,471	C/T	—	benign
rs746070827	7:4,006,952	A/G	—	likely benign
rs756282581	7:4,006,953	T/C	—	uncertain significance
rs146021666	7:4,006,955	G/A	—	uncertain significance
rs1340077145	7:4,006,970	C/G	—	uncertain significance
rs35393929	7:4,006,973	C/T	—	uncertain significance

Showing 100 of 275 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.