SLC22A11
solute carrier family 22 member 11
Summary
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Known Variants43 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs141159367 | 11:64,323,476 | C/T | — | likely benign |
| rs72559736 | 11:64,323,507 | C/T | — | benign |
| rs77872171 | 11:64,323,534 | G/A | — | benign |
| rs2038449144 | 11:64,323,539 | C/T | — | uncertain significance |
| rs183883961 | 11:64,323,601 | A/T | — | uncertain significance |
| rs200593751 | 11:64,323,607 | G/A | — | uncertain significance |
| rs35008345 | 11:64,323,613 | C/T | — | likely benign |
| rs781409853 | 11:64,323,700 | G/A | — | uncertain significance |
| rs763597613 | 11:64,323,715 | C/A | — | uncertain significance |
| rs749338954 | 11:64,323,790 | G/A | — | uncertain significance |
| rs200647534 | 11:64,323,833 | G/T | — | uncertain significance |
| rs150061096 | 11:64,323,838 | G/A | — | uncertain significance |
| rs563059719 | 11:64,326,667 | G/A | — | uncertain significance |
| rs374679250 | 11:64,329,490 | C/T | — | uncertain significance |
| rs35464738 | 11:64,329,527 | G/A | — | likely benign |
| rs552302187 | 11:64,329,544 | T/C | — | uncertain significance |
| rs756040639 | 11:64,329,576 | C/T | — | uncertain significance |
| rs765739605 | 11:64,329,603 | G/A | — | uncertain significance |
| rs367925828 | 11:64,329,803 | C/A | — | uncertain significance |
| rs150160581 | 11:64,329,804 | G/C | — | uncertain significance |
| rs138399841 | 11:64,329,814 | C/T | — | uncertain significance |
| rs17300741 | 11:64,331,462 | A/T | — | — |
| rs17372915 | 11:64,331,568 | G/T | — | — |
| rs761861029 | 11:64,331,796 | G/A | — | uncertain significance |
| rs142048527 | 11:64,331,799 | C/T | — | uncertain significance |
| rs773338608 | 11:64,331,896 | T/C | — | uncertain significance |
| rs372929612 | 11:64,332,769 | C/T | — | uncertain significance |
| rs75933978 | 11:64,332,779 | G/T | — | likely benign |
| rs963041074 | 11:64,332,793 | G/A | — | uncertain significance |
| rs71456318 | 11:64,332,862 | A/C | regulatory region variant | — |
| rs2078267 | 11:64,334,114 | C/T | regulatory region variant | — |
| rs1196278072 | 11:64,335,088 | C/T | — | uncertain significance |
| rs747047045 | 11:64,335,217 | G/A | — | uncertain significance |
| rs781432075 | 11:64,336,145 | T/G | — | uncertain significance |
| rs1591377207 | 11:64,336,151 | C/A | — | uncertain significance |
| rs140989947 | 11:64,336,157 | G/A | — | uncertain significance |
| rs2495438959 | 11:64,336,195 | A/T | — | uncertain significance |
| rs753181194 | 11:64,337,129 | C/G | — | uncertain significance |
| rs770866086 | 11:64,337,236 | G/A | — | uncertain significance |
| rs144573306 | 11:64,337,297 | C/T | — | uncertain significance |
| rs1383027723 | 11:64,337,305 | G/A | — | uncertain significance |
| rs1393919767 | 11:64,337,317 | G/T | — | uncertain significance |
| rs557911790 | 11:64,338,476 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.