Trait
SNPs associated with Gout
648 genetic variants across 180 genes have been associated with Gout in published research. Key genes include A1CF, AAK1, ABCA6.
Associated variants648 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2728099 | — | GWAS association (p=4.9e-324) | Meta-analysis |
| rs1171614 | SLC16A9 | GWAS association (p=2.0e-90) | Meta-analysis |
| rs9847710 | SFMBT1 | GWAS association (p=3.0e-76) | Meta-analysis |
| rs13246993 | MLXIPL | GWAS association (p=2.0e-58) | Meta-analysis |
| rs1165199 | SLC17A1 | GWAS association (p=8.0e-57) | Meta-analysis |
| rs4646776 | ALDH2 | GWAS association (p=4.0e-51) | Meta-analysis |
| rs2229357 | INHBC | GWAS association (p=4.0e-49) | Meta-analysis |
| rs2070803 | TRIM46 | GWAS association (p=7.0e-36) | Meta-analysis |
| rs114165349 | — | GWAS association (p=1.0e-24) | Meta-analysis |
| rs12437816 | FBXO22 | GWAS association (p=3.0e-18) | Meta-analysis |
| rs12129861 | PDZK1 | GWAS association (p=7.0e-18) | Meta-analysis |
| rs16856530 | LRP2 | GWAS association (p=5.0e-13) | Meta-analysis |
| rs4515883 | SHLD2 | GWAS association (p=2.0e-12) | Meta-analysis |
| rs117564322 | — | GWAS association (p=3.0e-09) | Meta-analysis |
| rs1260326 | GCKR | GWAS association (p=5.0e-166) | Meta-analysis |
| rs3747207 | PNPLA3 | GWAS association (p=3.0e-24) | Meta-analysis |
| rs9895661 | BCAS3 | GWAS association (p=7.0e-27) | Meta-analysis |
| rs1481012 | ABCG2 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs10805346 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs2725217 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs2728109 | PKD2 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs13129697 | SLC2A9 | GWAS association (p=4.0e-157) | Major Consortium Study |
| rs2817188 | — | GWAS association (p=5.0e-79) | Major Consortium Study |
| rs2581817 | SFMBT1 | GWAS association (p=2.0e-76) | Major Consortium Study |
| rs9426886 | TRIM46 | GWAS association (p=2.0e-69) | Major Consortium Study |
| rs11264341 | TRIM46 | GWAS association (p=3.0e-64) | Major Consortium Study |
| rs1171616 | — | GWAS association (p=4.0e-53) | Major Consortium Study |
| rs2268374 | LRP2 | GWAS association (p=6.0e-50) | Major Consortium Study |
| rs10851885 | — | GWAS association (p=2.0e-49) | Major Consortium Study |
| rs17632159 | LOC105379030 | GWAS association (p=9.0e-44) | Major Consortium Study |
| rs11609805 | — | GWAS association (p=4.0e-43) | Major Consortium Study |
| rs4693211 | — | GWAS association (p=2.0e-42) | Major Consortium Study |
| rs11604568 | — | GWAS association (p=4.0e-38) | Major Consortium Study |
| rs2078267 | SLC22A11 | GWAS association (p=2.0e-37) | Major Consortium Study |
| rs1165196 | SLC17A1 | GWAS association (p=5.0e-36) | Major Consortium Study |
| rs11636251 | NRG4 | GWAS association (p=4.0e-34) | Major Consortium Study |
| rs11172181 | R3HDM2 | GWAS association (p=4.0e-34) | Major Consortium Study |
| rs28807822 | BICC1 | GWAS association (p=9.0e-34) | Major Consortium Study |
| rs149675351 | BICC1 | GWAS association (p=2.0e-33) | Major Consortium Study |
| rs35173225 | — | GWAS association (p=2.0e-30) | Major Consortium Study |
| rs2244552 | SFMBT1 | GWAS association (p=5.0e-30) | Major Consortium Study |
| rs10224210 | — | GWAS association (p=8.0e-30) | Major Consortium Study |
| rs4971100 | — | GWAS association (p=1.0e-29) | Major Consortium Study |
| rs2075252 | LRP2 | GWAS association (p=2.0e-29) | Major Consortium Study |
| rs13234378 | MLXIPL | GWAS association (p=2.0e-29) | Major Consortium Study |
| rs10821905 | A1CF | GWAS association (p=5.0e-28) | Major Consortium Study |
| rs10265221 | — | GWAS association (p=6.0e-27) | Major Consortium Study |
| rs6839820 | — | GWAS association (p=8.0e-27) | Major Consortium Study |
| rs75460349 | — | GWAS association (p=8.0e-27) | Major Consortium Study |
| rs114791459 | — | GWAS association (p=5.0e-26) | Major Consortium Study |
| rs16890979 | SLC2A9 | GWAS association (p=5.0e-26) | Major Consortium Study |
| rs11755724 | RREB1 | GWAS association (p=1.0e-25) | Major Consortium Study |
| rs738409 | PNPLA3 | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs13240065 | MLXIPL | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs6464165 | PRKAG2 | GWAS association (p=5.0e-24) | Major Consortium Study |
| rs16869379 | — | GWAS association (p=5.0e-23) | Major Consortium Study |
| rs1229984 | ADH1B | GWAS association (p=5.0e-23) | Major Consortium Study |
| rs2611336 | ZNF318 | GWAS association (p=1.0e-22) | Major Consortium Study |
| rs114580333 | — | GWAS association (p=1.0e-21) | Major Consortium Study |
| rs4783580 | — | GWAS association (p=1.0e-21) | Major Consortium Study |
| rs9296413 | — | GWAS association (p=1.0e-21) | Major Consortium Study |
| rs3812316 | MLXIPL | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs552615101 | AKT1S1 | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs13120400 | ABCG2 | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs1967017 | — | GWAS association (p=5.0e-21) | Major Consortium Study |
| rs28793136 | — | GWAS association (p=5.0e-20) | Major Consortium Study |
| rs1171619 | — | GWAS association (p=7.0e-20) | Major Consortium Study |
| rs7193778 | — | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs12908437 | — | GWAS association (p=9.0e-19) | Major Consortium Study |
| rs471618 | NRXN2 | GWAS association (p=2.0e-18) | Major Consortium Study |
| rs1896246 | BICC1 | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs4398731 | — | GWAS association (p=5.0e-18) | Major Consortium Study |
| rs10995527 | JMJD1C | GWAS association (p=6.0e-18) | Major Consortium Study |
| rs963837 | LINC02859 | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs4966021 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs2728127 | — | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs75341455 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs10942549 | — | GWAS association (p=8.0e-17) | Major Consortium Study |
| rs6759013 | LRP2 | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs7672194 | ABCG2 | GWAS association (p=2.0e-16) | Major Consortium Study |
| rs11227299 | — | GWAS association (p=1.0e-15) | Major Consortium Study |
| rs6760274 | — | GWAS association (p=3.0e-15) | Major Consortium Study |
| rs7200764 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs6548238 | — | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs2581778 | SFMBT1 | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs114146907 | — | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs884302 | HLF | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs760077 | MTX1 | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs2286276 | TBL2 | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs77085155 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs13140984 | — | GWAS association (p=5.0e-13) | Major Consortium Study |
| rs9287058 | — | GWAS association (p=6.0e-13) | Major Consortium Study |
| rs532582234 | — | GWAS association (p=7.0e-13) | Major Consortium Study |
| rs4575545 | MAFTRR | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs10767873 | LOC101928338 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs10852974 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs4962696 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs157934 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs28548845 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs16891234 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
Showing the top 100 of 648 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.