rs9847710
This variant is located in the SFMBT1 gene.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
gout
Major TJ et al. “A genome-wide association analysis reveals new pathogenic pathways in gout.” Nature Genetics 56(11):2392-2406 (2024)
Allele T
OR 0.91
p 3.0e-76
N 2,206,883
Large GWAS
European
Zhou W et al. “Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.” Cell Genomics 2(10):100192 (2022)
Allele T
OR 0.08
p 1.0e-20
N 1,485,233
Meta-analysisLarge GWAS
multi-ancestry
Sumpter NA et al. “Association of Gout Polygenic Risk Score With Age at Disease Onset and Tophaceous Disease in European and Polynesian Men With Gout.” Arthritis & Rheumatology (hoboken, N.j.) 75(5):816-825 (2023)
Allele T
OR 1.12
p 7.0e-11
N 332,370
Large GWAS
European
urate measurement
Gill D et al. “Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.” Hypertension (dallas, Tex. : 1979) 77(2):383-392 (2021)
Allele T
OR 0.03
p 3.0e-72
N 454,183
Meta-analysisLarge GWAS
European
hemorrhoid
Zheng T et al. “Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.” Gut 70(8):1538-49 (2021)
Allele T
OR 1.04
p 1.0e-23
N 944,133
Large GWAS
European
uric acid measurement
Park JS et al. “Genome-wide meta-analysis revealed several genetic loci associated with serum uric acid levels in Korean population: an analysis of Korea Biobank data.” Journal of Human Genetics 67(4):231-237 (2022)
Allele T
OR —
p 2.0e-11
N 60,585
Meta-analysisLarge GWAS
East Asian
ulcerative colitis
Jostins L et al. “Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.” Nature 491(7422):119-24 (2012)
Allele C
OR 1.06
p 1.0e-8
N 34,366
Large GWAS
European
About SFMBT1
This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]
View all SFMBT1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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